Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0JKYFC
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| ADC Name |
N-D4-1508
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| Synonyms |
N-D4 AZ-1508
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Antibody Name |
NIP228
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor (EGFR); Receptor tyrosine-protein kinase erbB-3 (ERBB3)
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Antigen Info | ||||
| Payload Name |
AZ-1508
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Cysteine D4
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through reduced inter-chain cysteines (Cys 239)
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