General Information of This Antibody-drug Conjugate (ID: DRG0IXDXJ)
ADC Name
BNT3212
Synonyms
BNT-3212; PM1300
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Organization
Biotheus (Originator);BioNTech (Originator)
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
8
Antibody Name
Anti-EGFR/HER3 bsAb
 Antibody Info 
Antigen Name
Epidermal growth factor receptor (EGFR); Receptor tyrosine-protein kinase erbB-3 (HER3)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07147348; CTR20253266