General Information of This Antibody-drug Conjugate (ID: DRG0IWQWQ)
ADC Name
DXC-014
Synonyms
DXC-014; DXC014
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Organization
Hangzhou DAC Biotechnology (DAC Biotech) (Originator)
Drug Status
Phase 1
Antibody Name
Anti-B7H3/PSMA bsAb
 Antibody Info 
Antigen Name
CD276 antigen; Glutamate carboxypeptidase 2 (FOLH1)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Undisclosed
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07177937; CTR20253645; ChiCTR2500110610
Lung cancer
1 Trials
Trial ID
NCT07177937; CTR20253645; ChiCTR2500110610
Melanoma
1 Trials
Trial ID
NCT07177937; CTR20253645; ChiCTR2500110610
Prostate cancer
1 Trials
Trial ID
NCT07177937; CTR20253645; ChiCTR2500110610