Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0IGVTS
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ADC Name |
Anti-CD74 ADC 16-5
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Synonyms |
Anti-CD74-ADC 16-5
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Organization |
Merck & Co., Inc.
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Drug Status |
Investigative
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Indication |
In total 3 Indication(s)
Diffuse large B-cell lymphoma [ICD11:2A81]
Investigative
Renal cell carcinoma [ICD11:2C90]
Investigative
Sezary syndrome [ICD11:2B02]
Investigative
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Drug-to-Antibody Ratio |
2
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Structure | ||||||
Antibody Name |
Anti-hCD74 LL1
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Antibody Info | ||||
Antigen Name |
HLA class II histocompatibility antigen gamma chain (CD74)
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Antigen Info | ||||
Payload Name |
Undisclosed
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Linker Name |
Anti-CD74 ADC 16-5 linker
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Conjugate Type |
The drug linker was conjugated to the unnatural amino acid (UAA) para-azido phenylalanine (p-AF)
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