Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)

ADC ID	DRG0HTEZN
ADC Name	hCL1d-LC-G2-PNU
Synonyms	hCL1d-LC-G2-PNU Click to Show/Hide
Organization	SOTIO BIOTECH A.S
Drug Status	Investigative
Antibody Name	hCL1d	Antibody Info
Antigen Name	Claudin-18.2 (CLDN18.2)	Antigen Info
Payload Name	Undisclosed	Payload Info
Linker Name	Undisclosed

General Information of The Activity Data Related to This ADC

Revealed Based on the Cell Line Data

Click To Hide/Show 2 Activity Data Related to This Level

Standard Type	Value	Units	Cell Line	Disease Model
Half Maximal Effective Concentration (EC50)	0.5411	ug/ml	CVCL_0063	Normal
Half Maximal Effective Concentration (EC50)	0.5411	ug/ml	CVCL_0063	Normal

Full List of Activity Data of This Antibody-drug Conjugate

Revealed Based on the Cell Line Data

Click To Hide/Show 2 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	0.5411 ug/ml	High Claudin-18.2 expression (Claudin-18.2 +++)
Method Description	A Cell line test on HEK293T
In Vitro Model	Normal	HEK293T cells		CVCL_0063
Experiment 2 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	0.5411 ug/ml	High Claudin-18.2 expression (Claudin-18.2 +++)
Method Description	A Cell line test on HEK293T
In Vitro Model	Normal	HEK293T cells		CVCL_0063

References

Ref 1	Tumor-specific claudin 18.2 antibody-drug complex