General Information of This Antibody-drug Conjugate (ID: DRG0HOXGC)
ADC Name
SHR-1681
Synonyms
SHR-1681
   Click to Show/Hide
Organization
Jiangsu Hengrui Pharmaceuticals (Originator)
Drug Status
Phase 1/2
Antibody Name
Anti-HER3/c-Met bsAb
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3); Hepatocyte growth factor receptor (MET)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Undisclosed
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT06737731; CTR20244759