General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0HCEIV
ADC Name
ES2994374T3 conjugate3
Synonyms
ES2994374T3 conjugate3
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Organization
VISTERRA, INC.
Drug Status
Investigative
Antibody Name
mAb001
 Antibody Info 
Antigen Name
Lipopolysaccharide O antigen (LPS O antigen)
 Antigen Info 
Payload Name
undisclosed
 Payload Info 
Linker Name
Undisclosed
General Information of The Activity Data Related to This ADC
Revealed Based on the Cell Line Data
Click To Hide/Show 2 Activity Data Related to This Level
Standard Type Value Units Cell Line Disease Model
Half Maximal inhibitory Concentration (lC50) 
3.1
ug/ml
Undisclosed
P. aeruginosa strains
Half Maximal inhibitory Concentration (lC50) 
6.3
ug/ml
Undisclosed
P. aeruginosa strains
Full List of Activity Data of This Antibody-drug Conjugate
Revealed Based on the Cell Line Data
Click To Hide/Show 2 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
3.1 ug/ml
Method Description
Conjugates were tested in Pae39324, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model P. aeruginosa strains Pae39324 .
Experiment 2 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
6.3 ug/ml
Method Description
Conjugates were tested in Pae27853, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model P. aeruginosa strains Pae27853 .
References
Ref 1 Antibody molecule-drug conjugates and uses thereof