General Information of This Antibody-drug Conjugate (ID: DRG0GQCHO)
ADC Name
HMBD-802
Synonyms
HMBD-802; CLIO-8221
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Organization
Hummingbird Bioscience (Originator);Callio Therapeutics
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
4+4
Antibody Name
Anti-HER2 mAb
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-2 (HER2)
 Antigen Info 
Payload Name
Exatecan; ATR inhibitor
 Payload Info 
Payload Target
ATR+DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT07300943