General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0FYWIR
ADC Name
SKB103
Synonyms
SKB103; SKB 103
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Organization
Kelun Biotherapeutics (Originator);Merck & Co. (Top20 MNC)
Drug Status
Phase 1/2
Antibody Name
Anti-PD-L1 antibody
 Antibody Info 
Antigen Name
Programmed cell death ligand 1 (PD-L1); Leukocyte surface antigen CD47 (CD47)
 Antigen Info 
Payload Name
KL610348
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Kthiol (pyrimidine-thiol) AAA linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07459998; CTR20261135