General Information of This Antibody-drug Conjugate (ID: DRG0FQZSZ)
ADC Name
JSKN027
Synonyms
JSKN027
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Organization
Alphamab Oncology (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
4
Antibody Name
Anti-PDL1/TVEGFR2 bsAb
 Antibody Info 
Antigen Name
Programmed cell death 1 ligand 1 (PD-L1); Vascular endothelial growth factor A (VEGFA)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Enzymatic Catalysis
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07391644; CTR20260799
Colorectal cancer
1 Trials
Trial ID
NCT07391644; CTR20260799
Liver cancer
1 Trials
Trial ID
NCT07391644; CTR20260799
Lung cancer
1 Trials
Trial ID
NCT07391644; CTR20260799