General Information of This Antibody-drug Conjugate (ID: DRG0DWHZY)
ADC Name
SIM 0686
Synonyms
SIM 0686; SIM0686; SCR-A002
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Organization
Simcere Pharmaceutical Group (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
8
Antibody Name
Anti-FGFR2b IgG1 antibody
 Antibody Info 
Antigen Name
Fibroblast growth factor receptor 2 (FGFR2)
 Antigen Info 
Payload Name
CPT116
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT07050459; CTR20251415