Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0DWGFR
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| ADC Name |
mAb001-Conjugate1
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| Synonyms |
mAb001-Conjugate1
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| Organization |
VISTERRA, INC.
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| Drug Status |
Investigative
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| Antibody Name |
mAb001
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Antibody Info | ||||
| Antigen Name |
Lipopolysaccharide O antigen (LPS O antigen)
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Antigen Info | ||||
| Payload Name |
P295
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Payload Info | ||||
| Linker Name |
Undisclosed
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General Information of The Activity Data Related to This ADC
Revealed Based on the Cell Line Data
Full List of Activity Data of This Antibody-drug Conjugate
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
6.3 ug/ml
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| Method Description |
Conjugates were tested in BAA-2114, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
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| In Vitro Model | Pseudomonas aeruginosa (Schroeter) Migula | BAA-2114 | Pseudomonas aeruginosa (Schroeter) Migula | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
6.3 ug/ml
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| Method Description |
Conjugates were tested in BAA-2108, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
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| In Vitro Model | Pseudomonas aeruginosa (Schroeter) Migula | BAA-2108 | Pseudomonas aeruginosa (Schroeter) Migula | ||
| Experiment 3 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
12.5 ug/ml
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| Method Description |
Conjugates were tested in Pae27853, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
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| In Vitro Model | P. aeruginosa strains | Pae27853 | . | ||
| Experiment 4 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
12.5 ug/ml
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| Method Description |
Conjugates were tested in BAA-2110, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
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| In Vitro Model | Pseudomonas aeruginosa (Schroeter) Migula | BAA-2110 | Pseudomonas aeruginosa (Schroeter) Migula | ||