Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0DHVZJ
ADC Name
isumab04-C5
Synonyms
lsumab04-C5
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Organization
MURGITROYD & COMPANY
Drug Status
Investigative
Drug-to-Antibody Ratio
3.7
Antibody Name
Undisclosed
Antigen Name
Undisclosed
Payload Name
Compound 5
  Payload Info 
Therapeutic Target
DNA topoisomerase I (TOP1)
  Target Info 
Linker Name
Undisclosed
General Information of The Activity Data Related to This ADC
Revealed Based on the Cell Line Data
Click To Hide/Show 1 Activity Data Related to This Level
Standard Type Value Units Cell Line Disease Model
Half Maximal inhibitory Concentration (lC50) 
0.26
pM
CVCL_0218
Colon adenocarcinoma
Full List of Activity Data of This Antibody-drug Conjugate
Revealed Based on the Cell Line Data
Click To Hide/Show 1 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50) 0.26 pM High FRa expression (FRa +++)
Method Description
A Cell line test on Colo205
In Vitro Model Colon adenocarcinoma Colo205 cells CVCL_0218
References
Ref 1 Antibody-drug conjugate compounds, and methods of use and treatment