General Information of This Antibody-drug Conjugate (ID: DRG0CXRVR)
ADC Name
JSKN022
Synonyms
JSKN022
   Click to Show/Hide
Organization
Alphamab Oncology (Originator)
Drug Status
Phase 1
Drug-to-Antibody Ratio
4
Antibody Name
Anti-αvβ6/PDL1 bsAb
 Antibody Info 
Antigen Name
Integrin beta-6 (ITGB6); Programmed cell death 1 ligand 1 (PD-L1)
 Antigen Info 
Payload Name
Alphatecan (T01)
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Enzymatic Catalysis
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07292402; CTR20254082; ChiCTR2500110741