Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0AQIRQ
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
CN113286618A ADC-1
|
|||||
| Synonyms |
ADC-1
Click to Show/Hide
|
|||||
| Organization |
Medical Legal Person Foundation; Okayama University NUC
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
9.1
|
|||||
| Structure |
|
|||||
| Antibody Name |
alpha-HMGB1Ab
|
Antibody Info | ||||
| Antigen Name |
High mobility group box 1 protein (HMGB1)
|
Antigen Info | ||||
| Payload Name |
Doxorubicin
|
Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
|
Target Info | ||||
| Linker Name |
CN113286618A-ADC-1-linker
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
| Combination Type |
CN113286618A-ADC-1-linker-doxorubicin
|
|||||