Antigen Information
General Information of This Antigen (ID: TAR0ZYPEF)
| Antigen Name | C-C chemokine receptor type 7 (CCR7) |
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|---|---|---|---|---|---|---|
| Gene Name | CCR7 |
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| Gene ID | ||||||
| Synonym | CMKBR7; EBI1; EVI1; BLR2;CDw197;Epstein-Barr virus-induced G-protein coupled receptor 1;MIP-3 beta receptor;CD197 |
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| Sequence |
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWF
LPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAK SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV GIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMS FCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCEL SKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRH IRRSSMSVEAETTTTFSP Click to Show/Hide
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| Family | G-protein coupled receptor 1 family |
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| Function |
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
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| Uniprot Entry | ||||||
| HGNC ID | ||||||
| KEGG ID | ||||||
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
121G12
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
JBH492
|
DM4 |
Microtubule (MT) |
A cleavable linker |
Anti-CCR7 mAb 121G12
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Ab-MCC-DM1
[1]
|
Ab-MCC-DM1 payload |
Undisclosed |
Ab-MCC-DM1 linker |
|
|
Ab-SPDB-DM4
[1]
|
Ab-SPDB-DM4 payload |
Undisclosed |
Ab-SPDB-DM4 linker |
|
|
Ab-sSPDB-DM4
[1]
|
Ab-sSPDB-DM4 payload |
Undisclosed |
Ab-sSPDB-DM4 linker |
|
|
Ab-CX1-1-DM1
[1]
|
Ab-CX1-1-DM1 payload |
Undisclosed |
Ab-CX1-1-DM1 linker |
|
|
Ab-MPET-DM4
[1]
|
Ab-MPET-DM4 payload |
Undisclosed |
Ab-MPET-DM4 linker |
|
|
Ab-MPET-DM1
[1]
|
Ab-MPET-DM1 payload |
Undisclosed |
Ab-MPET-DM1 linker |
|
|
Ab-MBT-DM4
[1]
|
Ab-MBT.DM4 payload |
Undisclosed |
Ab-MBT.DM4 linker |
|
|
Ab-MBT-DM4
[1]
|
Ab-MBT-DM4 payload |
Undisclosed |
Ab-MBT-DM4 linker |
|
|
Ab-MEPET-DM4
[1]
|
Ab-MEPET-DM4 payload |
Undisclosed |
Ab-MEPET-DM4 linker |
|
|
Ab-MEPET-DM1
[1]
|
Ab-MEPET-DM1 payload |
Undisclosed |
Ab-MEPET-DM1 linker |
|
|
Ab-MEPET-DM3
[1]
|
Ab.MEPET.DM3 payload |
Undisclosed |
Ab.MEPET.DM3 linker |
|
|
Ab-MPET-DM4
[1]
|
Ab-MPET-DM4 payload |
Undisclosed |
Ab-MPET-DM4 linker |
|
|
121G12-CysMab-DAPA-MPET-DM4
[1]
|
121G12.CysMab.DAPA.MPET.DM4 payload |
Undisclosed |
121G12.CysMab.DAPA.MPET.DM4 linker |
|
|
121G12-DAPA-sSPDB-DM4
[1]
|
121G12.DAPA.sSPDB.DM4 payload |
Undisclosed |
121G12.DAPA.sSPDB.DM4 linker |
|
|
121G12-CysMab-DAPA-AURIX1
[1]
|
121G12.CysMab.DAPA.AURIX1 payload |
Undisclosed |
121G12.CysMab.DAPA.AURIX1 linker |
|
|
121G12-CysMab-AURIX1
[1]
|
121G12.CysMab.AURIX1 payload |
Undisclosed |
121G12.CysMab.AURIX1 linker |
Anti-CCR7 mAb 506E15
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
506E15-AURIX1
[1]
|
506E15.AURIX1 payload |
Undisclosed |
506E15.AURIX1 linker |
|
|
506E15-CysMab-DAPA-AURIX2
[1]
|
506E15.CysMab.DAPA.AURIX2 payload |
Undisclosed |
506E15.CysMab.DAPA.AURIX2 linker |
|
|
506E15-CysMab-AURIX1
[1]
|
506E15.CysMab.AURIX1 payload |
Undisclosed |
506E15.CysMab.AURIX1 linker |
Anti-CCR7 mAb 674J13
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
674J13-CysMab-AURIX1
[1]
|
674J13.CysMab.AURIX1 payload |
Undisclosed |
674J13.CysMab.AURIX1 linker |
|
|
674J13-CysMab-DAPA-AURIX2
[1]
|
674J13.CysMab.DAPA.AURIX2 payload |
Undisclosed |
674J13.CysMab.DAPA.AURIX2 linker |
Anti-CCR7 mAb 684E12
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
684E12-SMCC-DM1
[1]
|
684E12.SMCC.DM1 payload |
Undisclosed |
684E12.SMCC.DM1 linker |