General Information of This Antigen (ID: TAR0ROZDZ)
Antigen Name
Collectin-10 (COLEC10)
Gene Name
COLEC10
Gene ID
10584
Synonym
CLL1; UNQ366; PRO702; Collectin liver protein 1;Collectin-34
Sequence
MNGFASLLRRNQFILLVLFLLQIQSLGLDIDSRPTAEVCATHTISPGPKGDDGEKGDPGE
EGKHGKVGRMGPKGIKGELGDMGDQGNIGKTGPIGKKGDKGEKGLLGIPGEKGKAGTVCD
CGRYRKFVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRG
GMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPS
DPYGHEDCVEMLSSGRWNDTECHLTMYFVCEFIKKKK

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Family
Claudin family
Function
Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration.

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Uniprot Entry
COL10_HUMAN
HGNC ID
HGNC:2220
KEGG ID
hsa:10584
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
Human hCLL-1 Anti-ody genetically fused with CD38
ADC Name Payload Target Linker ADC Info
DAR2-ARC-ADC [1]
Monomethyl auristatin F
Microtubule (MT)
NAD-based dinucleotide linker
Undisclosed
ADC Name Payload Target Linker ADC Info
DAR4-ARC-ADC [1]
Monomethyl auristatin F
Microtubule (MT)
NAD-based dinucleotide linker
References
Ref 1 Site-specific antibody-drug conjugates with variable drug-to-antibody-ratios for AML therapy. J Control Release. 2021 Aug 10;336:433-442. doi: 10.1016/j.jconrel.2021.06.041. Epub 2021 Jun 29.