Antigen Information

General Information of This Antigen
Antigen ID
TAR0ROZDZ
Antigen Name
Collectin-10 (COLEC10)
Gene Name
COLEC10
Gene ID
10584
Synonym
CLL1; UNQ366; PRO702; Collectin liver protein 1;Collectin-34
Sequence
MNGFASLLRRNQFILLVLFLLQIQSLGLDIDSRPTAEVCATHTISPGPKGDDGEKGDPGE
EGKHGKVGRMGPKGIKGELGDMGDQGNIGKTGPIGKKGDKGEKGLLGIPGEKGKAGTVCD
CGRYRKFVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRG
GMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPS
DPYGHEDCVEMLSSGRWNDTECHLTMYFVCEFIKKKK

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Family
Claudin family
Function
Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration.

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Uniprot Entry
COL10_HUMAN
HGNC ID
HGNC:2220
KEGG ID
hsa:10584
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Human hCLL-1 Anti-ody genetically fused with CD38
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
DAR2-ARC-ADC
Monomethyl auristatin F
Microtubule (MT)
NAD-based dinucleotide linker
 [1]
Undisclosed
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
DAR4-ARC-ADC
Monomethyl auristatin F
Microtubule (MT)
NAD-based dinucleotide linker
 [1]
References
Ref 1 Site-specific antibody-drug conjugates with variable drug-to-antibody-ratios for AML therapy. J Control Release. 2021 Aug 10;336:433-442. doi: 10.1016/j.jconrel.2021.06.041. Epub 2021 Jun 29.