Antigen Information
General Information of This Antigen (ID: TAR0RBHCF)
| Antigen Name | Globo H (globotriaosylceramide) |
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|---|---|---|---|---|---|---|
| Function |
Globo H (globotriaosylceramide) is a global-series glycosphingolipid antigen that is present on the outer membrane of some cancer cells. Globo H is not expressed in normal tissue cells but is expressed in a number of types of cancers, including cancers of the breast, prostate, and pancreas. Globo H's exclusivity for cancer cells makes it a target of interest for cancer therapies.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
OBI-888
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
OBI-999
|
Monomethyl auristatin E |
Microtubule (MT) |
ThioBridge-PEG24-Val-Cit-PABC |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Globo-H ADC
[1]
|
Undisclosed |
Undisclosed |
Undisclosed |
References