Antigen Information

General Information of This Antigen
Antigen ID
TAR0NGRBV
Antigen Name
Leucine-rich alpha-2-glycoprotein (LRG1)
Gene Name
LRG1
Gene ID
116844
Synonym
LRG
Sequence
MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWGVTLSPKDCQVFRSDHGSSISCQPPA
EIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRV
LDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLP
PGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRY
LFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNP
WICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ

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Uniprot Entry
A2GL_HUMAN
HGNC ID
HGNC:29480
KEGG ID
hsa:116844
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Magacizumab
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
LRG1-ADC 5
Monomethyl auristatin E
Microtubule (MT)
Dipeptide-diBrPD (dibromopyridazinedione )
 [1]
 ADC Info 
Magacizumab PD-MMAE ADC 5
Monomethyl auristatin E
Microtubule (MT)
Mepstra-PD-PEG3-Mal-Cit-PABC
 [1]
References
Ref 1 Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target. RSC Chem Biol. 2021 May 31;2(4):1206-1220.