Antigen Information
General Information of This Antigen (ID: TAR0NGRBV)
| Antigen Name | Leucine-rich alpha-2-glycoprotein (LRG1) |
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|---|---|---|---|---|---|---|
| Gene Name | LRG1 |
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| Gene ID | ||||||
| Synonym | LRG |
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| Sequence |
MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWGVTLSPKDCQVFRSDHGSSISCQPPA
EIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRV LDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLP PGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRY LFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNP WICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ Click to Show/Hide
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| Uniprot Entry | ||||||
| HGNC ID | ||||||
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Magacizumab
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
LRG1-ADC 5
[1]
|
Monomethyl auristatin E |
Microtubule (MT) |
Dipeptide-diBrPD (dibromopyridazinedione ) |
|
|
Magacizumab PD-MMAE ADC 5
[1]
|
Monomethyl auristatin E |
Microtubule (MT) |
Mepstra-PD-PEG3-Mal-Cit-PABC |
References