Antigen Information

General Information of This Antigen
Antigen ID
TAR0KDKED
Antigen Name
Urokinase-type plasminogen activator (Plau)
Gene Name
Plau
Synonym
Plau
Sequence
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL

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Family
Peptidase S1 family
Function
FUNCTION: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

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Uniprot Entry
UROK_HUMAN
HGNC ID
HGNC:9052 ,
KEGG ID
hsa:5328 ,
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
FL1-PNU
Undisclosed
Undisclosed
DBCO-PEG4-Val-Cit-PABC
 [1]
References
Ref 1 Targeting uPAR with an antibody-drug conjugate suppresses tumor growth and reshapes the immune landscape in pancreatic cancer models