Antigen Information
General Information of This Antigen (ID: TAR0HXNLQ)
| Antigen Name | Amphiregulin (AREG) |
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| Gene Name | AREG |
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| Gene ID | ||||||
| Synonym | Colorectum cell-derived growth factor |
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| Sequence |
MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSG
SEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENT SDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGER CGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKK LRQENGNVHAIA Click to Show/Hide
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| Family | Alpha-carbonic anhydrase family |
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| Function |
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of .get cells including astrocytes, Schwann cells and fibroblasts.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
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Anti-cleaved-AREG 1A3 Anti-ody
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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GMF-1A3-MMAE
[1]
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Monomethyl auristatin E |
Microtubule (MT) |
Mc-Val-Cit-PABC |
References