Antigen Information
General Information of This Antigen
Antigen ID | TAR0GFSKS |
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Antigen Name | Ephrin type-A receptor 2 (EPHA2) |
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Gene Name | EPHA2 |
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Gene ID | ||||||
Synonym | ECK; Epithelial cell kinase;Tyrosine-protein kinase receptor ECK |
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Sequence |
MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMN
DMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFN LYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYL AFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGG EEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPS PEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDI VYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSG LVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGG VAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQA VLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDF LGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGML RGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIP IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPM DCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSG SEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAY SLLGLKDQVNTVGIPI Click to Show/Hide
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Family | Tyr protein family |
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Function |
Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin- A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand- independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
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Uniprot Entry | ||||||
HGNC ID | ||||||
KEGG ID |
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-EPHA2 mAb
ADC Info | ADC Name | Payload | Target | Linker | Ref |
---|---|---|---|---|---|
EphA2-targeted mAb ADC 144 |
EphA2-targeted mAb ADC 144 payload |
Undisclosed |
EphA2-targeted mAb ADC 144 linker |
[1] | |
EphA2-targeted mAb ADC 145 |
EphA2-targeted mAb ADC 145 payload |
Undisclosed |
EphA2-targeted mAb ADC 145 linker |
[1] | |
EphA2-targeted mAb ADC 146 |
EphA2-targeted mAb ADC 146 payload |
Undisclosed |
EphA2-targeted mAb ADC 146 linker |
[1] | |
EphA2-targeted mAb ADC 147 |
EphA2-targeted mAb ADC 147 payload |
Undisclosed |
EphA2-targeted mAb ADC 147 linker |
[1] | |
EphA2-targeted mAb ADC 148 |
EphA2-targeted mAb ADC 148 payload |
Undisclosed |
EphA2-targeted mAb ADC 148 linker |
[1] | |
EphA2-targeted mAb ADC 149 |
EphA2-targeted mAb ADC 149 payload |
Undisclosed |
EphA2-targeted mAb ADC 149 linker |
[1] | |
EphA2-targeted mAb ADC 150 |
EphA2-targeted mAb ADC 150 payload |
Undisclosed |
EphA2-targeted mAb ADC 150 linker |
[1] | |
EphA2-targeted mAb ADC 151 |
EphA2-targeted mAb ADC 151 payload |
Undisclosed |
EphA2-targeted mAb ADC 151 linker |
[1] | |
EphA2-targeted mAb ADC 152 |
EphA2-targeted mAb ADC 152 payload |
Undisclosed |
EphA2-targeted mAb ADC 152 linker |
[1] | |
EphA2-targeted mAb ADC A 12 (DAR8) |
EphA2-targeted mAb ADC A 12 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 12 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 12 (DAR4) |
EphA2-targeted mAb ADC A 12 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 12 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 17 (DAR8) |
EphA2-targeted mAb ADC A 17 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 17 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 17 (DAR4) |
EphA2-targeted mAb ADC A 17 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 17 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 21 (DAR8) |
EphA2-targeted mAb ADC A 21 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 21 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 21 (DAR4) |
EphA2-targeted mAb ADC A 21 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 21 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 22 (DAR6) |
EphA2-targeted mAb ADC A 22 (DAR6) payload |
Undisclosed |
EphA2-targeted mAb ADC A 22 (DAR6) linker |
[1] | |
EphA2-targeted mAb ADC A 22 (DAR2) |
EphA2-targeted mAb ADC A 22 (DAR2) payload |
Undisclosed |
EphA2-targeted mAb ADC A 22 (DAR2) linker |
[1] | |
EphA2-targeted mAb ADC A 19 (DAR8) |
EphA2-targeted mAb ADC A 19 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 19 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 19 (DAR4) |
EphA2-targeted mAb ADC A 19 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 19 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 20 (DAR8) |
EphA2-targeted mAb ADC A 20 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 20 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 20 (DAR4) |
EphA2-targeted mAb ADC A 20 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 20 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 24 (DAR8) |
EphA2-targeted mAb ADC A 24 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 24 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 24 (DAR4) |
EphA2-targeted mAb ADC A 24 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 24 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC A 23 (DAR8) |
EphA2-targeted mAb ADC A 23 (DAR8) payload |
Undisclosed |
EphA2-targeted mAb ADC A 23 (DAR8) linker |
[1] | |
EphA2-targeted mAb ADC A 23 (DAR4) |
EphA2-targeted mAb ADC A 23 (DAR4) payload |
Undisclosed |
EphA2-targeted mAb ADC A 23 (DAR4) linker |
[1] | |
EphA2-targeted mAb ADC 11 |
EphA2-targeted mAb ADC 11 payload |
Undisclosed |
EphA2-targeted mAb ADC 11 linker |
[1] | |
EphA2-targeted mAb ADC 17 |
EphA2-targeted mAb ADC 17 payload |
Undisclosed |
EphA2-targeted mAb ADC 17 linker |
[1] | |
EphA2-targeted mAb ADC 19 |
EphA2-targeted mAb ADC 19 payload |
Undisclosed |
EphA2-targeted mAb ADC 19 linker |
[1] | |
EphA2-targeted mAb ADC 20 |
EphA2-targeted mAb ADC 20 payload |
Undisclosed |
EphA2-targeted mAb ADC 20 linker |
[1] | |
EphA2-targeted mAb ADC 21 |
EphA2-targeted mAb ADC 21 payload |
Undisclosed |
EphA2-targeted mAb ADC 21 linker |
[1] | |
EphA2-targeted mAb ADC 22 |
EphA2-targeted mAb ADC 22 payload |
Undisclosed |
EphA2-targeted mAb ADC 22 linker |
[1] | |
EphA2-targeted mAb ADC 23 |
EphA2-targeted mAb ADC 23 payload |
Undisclosed |
EphA2-targeted mAb ADC 23 linker |
[1] | |
EphA2-targeted mAb ADC 24 |
EphA2-targeted mAb ADC 24 payload |
Undisclosed |
EphA2-targeted mAb ADC 24 linker |
[1] | |
EphA2-targeted mAb ADC 25 |
EphA2-targeted mAb ADC 25 payload |
Undisclosed |
EphA2-targeted mAb ADC 25 linker |
[1] | |
EphA2-targeted mAb ADC 26 |
EphA2-targeted mAb ADC 26 payload |
Undisclosed |
EphA2-targeted mAb ADC 26 linker |
[1] | |
EphA2-targeted mAb ADC 27 |
EphA2-targeted mAb ADC 27 payload |
Undisclosed |
EphA2-targeted mAb ADC 27 linker |
[1] | |
EphA2-targeted mAb ADC 66 |
EphA2-targeted mAb ADC 66 payload |
Undisclosed |
EphA2-targeted mAb ADC 66 linker |
[1] | |
EphA2-targeted mAb ADC 67 |
EphA2-targeted mAb ADC 67 payload |
Undisclosed |
EphA2-targeted mAb ADC 67 linker |
[1] | |
EphA2-targeted mAb ADC 68 |
EphA2-targeted mAb ADC 68 payload |
Undisclosed |
EphA2-targeted mAb ADC 68 linker |
[1] | |
EphA2-targeted mAb ADC 69 |
EphA2-targeted mAb ADC 69 payload |
Undisclosed |
EphA2-targeted mAb ADC 69 linker |
[1] | |
EphA2-targeted mAb ADC 96 |
EphA2-targeted mAb ADC 96 payload |
Undisclosed |
EphA2-targeted mAb ADC 96 linker |
[1] | |
EphA2-targeted mAb ADC 98 |
EphA2-targeted mAb ADC 98 payload |
Undisclosed |
EphA2-targeted mAb ADC 98 linker |
[1] | |
EphA2-targeted mAb ADC 101 |
EphA2-targeted mAb ADC 101 payload |
Undisclosed |
EphA2-targeted mAb ADC 101 linker |
[1] | |
EphA2-targeted mAb ADC 102 |
EphA2-targeted mAb ADC 102 payload |
Undisclosed |
EphA2-targeted mAb ADC 102 linker |
[1] | |
EphA2-targeted mAb ADC 103 |
EphA2-targeted mAb ADC 103 payload |
Undisclosed |
EphA2-targeted mAb ADC 103 linker |
[1] | |
EphA2-targeted mAb ADC 104 |
EphA2-targeted mAb ADC 104 payload |
Undisclosed |
EphA2-targeted mAb ADC 104 linker |
[1] | |
EphA2-targeted mAb ADC 105 |
EphA2-targeted mAb ADC 105 payload |
Undisclosed |
EphA2-targeted mAb ADC 105 linker |
[1] | |
EphA2-targeted mAb ADC 106 |
EphA2-targeted mAb ADC 106 payload |
Undisclosed |
EphA2-targeted mAb ADC 106 linker |
[1] | |
EphA2-targeted mAb ADC 107 |
EphA2-targeted mAb ADC 107 payload |
Undisclosed |
EphA2-targeted mAb ADC 107 linker |
[1] | |
EphA2-targeted mAb ADC 108 |
EphA2-targeted mAb ADC 108 payload |
Undisclosed |
EphA2-targeted mAb ADC 108 linker |
[1] | |
EphA2-targeted mAb ADC 109 |
EphA2-targeted mAb ADC 109 payload |
Undisclosed |
EphA2-targeted mAb ADC 109 linker |
[1] | |
EphA2-targeted mAb ADC 110 |
EphA2-targeted mAb ADC 110 payload |
Undisclosed |
EphA2-targeted mAb ADC 110 linker |
[1] | |
EphA2-targeted mAb ADC 111 |
EphA2-targeted mAb ADC 111 payload |
Undisclosed |
EphA2-targeted mAb ADC 111 linker |
[1] | |
EphA2-targeted mAb ADC 112 |
EphA2-targeted mAb ADC 112 payload |
Undisclosed |
EphA2-targeted mAb ADC 112 linker |
[1] | |
EphA2-targeted mAb ADC 121 |
EphA2-targeted mAb ADC 121 payload |
Undisclosed |
EphA2-targeted mAb ADC 121 linker |
[1] | |
EphA2-targeted mAb ADC 122 |
EphA2-targeted mAb ADC 122 payload |
Undisclosed |
EphA2-targeted mAb ADC 122 linker |
[1] | |
EphA2-targeted mAb ADC 123 |
EphA2-targeted mAb ADC 123 payload |
Undisclosed |
EphA2-targeted mAb ADC 123 linker |
[1] | |
EphA2-targeted mAb ADC 124 |
EphA2-targeted mAb ADC 124 payload |
Undisclosed |
EphA2-targeted mAb ADC 124 linker |
[1] | |
EphA2-targeted mAb ADC 125 |
EphA2-targeted mAb ADC 125 payload |
Undisclosed |
EphA2-targeted mAb ADC 125 linker |
[1] | |
EphA2-targeted mAb ADC 126 |
EphA2-targeted mAb ADC 126 payload |
Undisclosed |
EphA2-targeted mAb ADC 126 linker |
[1] | |
EphA2-targeted mAb ADC 128 |
EphA2-targeted mAb ADC 128 payload |
Undisclosed |
EphA2-targeted mAb ADC 128 linker |
[1] | |
EphA2-targeted mAb ADC 131 |
EphA2-targeted mAb ADC 131 payload |
Undisclosed |
EphA2-targeted mAb ADC 131 linker |
[1] | |
EphA2-targeted mAb ADC 133 |
EphA2-targeted mAb ADC 133 payload |
Undisclosed |
EphA2-targeted mAb ADC 133 linker |
[1] | |
EphA2-targeted mAb ADC 134 |
EphA2-targeted mAb ADC 134 payload |
Undisclosed |
EphA2-targeted mAb ADC 134 linker |
[1] |
Anti-EPHA2 mAb 1C1
ADC Info | ADC Name | Payload | Target | Linker | Ref |
---|---|---|---|---|---|
1C1-mcMMAF |
Monomethyl auristatin F |
Microtubule (MT) |
Maleimido-caproyl |
[2] | |
CN106459205B ADC-1 |
CN106459205B ADC-1 payload |
Undisclosed |
CN106459205B ADC-1 linker |
[3] | |
CN106459205B ADC-2 |
CN106459205B ADC-2 payload |
Undisclosed |
CN106459205B ADC-2 linker |
[3] | |
CN106459205B ADC-3 |
CN106459205B ADC-3 payload |
Undisclosed |
CN106459205B ADC-3 linker |
[3] | |
CN106459205B ADC-4 |
CN106459205B ADC-4 payload |
Undisclosed |
CN106459205B ADC-4 linker |
[3] | |
CN106459205B ADC-5 |
CN106459205B ADC-5 payload |
Undisclosed |
CN106459205B ADC-5 linker |
[3] | |
MEDI-547 |
Monomethyl auristatin F |
Microtubule (MT) |
Maleimido-caproyl |
[4] |
Undisclosed
ADC Info | ADC Name | Payload | Target | Linker | Ref |
---|---|---|---|---|---|
SAB-Y9-59 |
Undisclosed |
Undisclosed |
Undisclosed |
[5] | |
ATRC-301 |
Undisclosed |
Undisclosed |
Undisclosed |
[6] | |
SAB-Y20 |
Undisclosed |
Undisclosed |
Undisclosed |
[7] | |
SAB-Y19 |
Undisclosed |
Undisclosed |
Undisclosed |
[8] | |
MM-310 |
Docetaxel |
Microtubule (MT) |
Undisclosed |
[9] |
Tissue/Disease specific Abundances of This Antigen
Tissue specific Abundances of This Antigen
ICD Disease Classification 01
Bacterial infection [ICD-11: 1A00-1C4Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Gingival | |
The Specific Disease | Bacterial infection of gingival | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.096046332; Fold-change: 0.150150832; Z-score: 0.274394416 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 02
Brain cancer [ICD-11: 2A00]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Brainstem | |
The Specific Disease | Glioma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.763217895; Fold-change: -0.403054274; Z-score: -0.339385341 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | White matter | |
The Specific Disease | Glioma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.964648746; Fold-change: -0.007659103; Z-score: -0.010233824 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Brainstem | |
The Specific Disease | Neuroectodermal tumor | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.27E-10; Fold-change: 0.909386817; Z-score: 3.176132127 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Nervous | |
The Specific Disease | Brain cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.96E-54; Fold-change: 0.515284879; Z-score: 0.97859663 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Chronic myeloid leukemia [ICD-11: 2A20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Polycythemia vera | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000151275; Fold-change: 0.119460046; Z-score: 0.791611726 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Whole blood | |
The Specific Disease | Myelofibrosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.268842068; Fold-change: 0.02301805; Z-score: 0.144429436 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
MyeloDysplastic syndromes [ICD-11: 2A37]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bone marrow | |
The Specific Disease | Myelodysplastic syndromes | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.033262676; Fold-change: 0.001341491; Z-score: 0.00816472 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.734162386; Fold-change: 0.004985145; Z-score: 0.042725718 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Lymphoma [ICD-11: 2A90- 2A85]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Tonsil | |
The Specific Disease | Lymphoma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.955827099; Fold-change: 0.029914328; Z-score: 0.104537913 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Gastric cancer [ICD-11: 2B72]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Gastric | |
The Specific Disease | Gastric cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.030242485; Fold-change: 1.686112015; Z-score: 3.365209999 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.062176972; Fold-change: 0.51050761; Z-score: 0.690872767 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Colon cancer [ICD-11: 2B90]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Colon | |
The Specific Disease | Colon cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.57E-32; Fold-change: 1.283315881; Z-score: 1.452041355 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.84E-05; Fold-change: 0.7295986; Z-score: 0.620189614 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Pancreatic cancer [ICD-11: 2C10]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Pancreas | |
The Specific Disease | Pancreatic cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000325935; Fold-change: 1.019518273; Z-score: 1.281878569 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 2.28E-24; Fold-change: 1.25881328; Z-score: 2.219117699 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Liver cancer [ICD-11: 2C12]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Liver | |
The Specific Disease | Liver cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000259177; Fold-change: -0.56704047; Z-score: -0.890202045 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 7.10E-53; Fold-change: -1.347903429; Z-score: -1.756350842 | |
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 0.003189438; Fold-change: -1.177245656; Z-score: -3.781115183 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Lung cancer [ICD-11: 2C25]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Lung | |
The Specific Disease | Lung cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.82225585; Fold-change: 0.160661098; Z-score: 0.223477587 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.14E-06; Fold-change: -0.226423005; Z-score: -0.280180599 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Melanoma [ICD-11: 2C30]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Melanoma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.546886402; Fold-change: -0.116106771; Z-score: -0.108351155 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Sarcoma [ICD-11: 2C35]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Muscle | |
The Specific Disease | Sarcoma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.31E-30; Fold-change: 0.381434949; Z-score: 1.235977447 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.202922266; Fold-change: 0.281165881; Z-score: 0.871448323 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Breast cancer [ICD-11: 2C60]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Breast | |
The Specific Disease | Breast cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.28E-82; Fold-change: -0.922451591; Z-score: -1.916744845 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.28E-08; Fold-change: -0.717836389; Z-score: -1.118067559 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Ovarian cancer [ICD-11: 2C73]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Ovarian | |
The Specific Disease | Ovarian cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.02E-05; Fold-change: 1.212928665; Z-score: 2.34625276 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.006092483; Fold-change: -0.666818612; Z-score: -0.797283224 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Cervical cancer [ICD-11: 2C77]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Cervical | |
The Specific Disease | Cervical cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.009640741; Fold-change: -0.566409161; Z-score: -0.821742345 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Uterine cancer [ICD-11: 2C78]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Endometrium | |
The Specific Disease | Uterine cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000930541; Fold-change: 0.601077843; Z-score: 0.493003443 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.002164197; Fold-change: -1.935652377; Z-score: -3.360363173 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Prostate cancer [ICD-11: 2C82]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Prostate | |
The Specific Disease | Prostate cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.051968678; Fold-change: -0.482419872; Z-score: -0.630347461 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Bladder cancer [ICD-11: 2C94]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bladder | |
The Specific Disease | Bladder cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.27E-19; Fold-change: 1.613338259; Z-score: 10.05119618 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Retina cancer [ICD-11: 2D02]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Uvea | |
The Specific Disease | Retinoblastoma tumor | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000143411; Fold-change: 1.103775523; Z-score: 2.095878728 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Thyroid cancer [ICD-11: 2D10]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Thyroid | |
The Specific Disease | Thyroid cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.08E-20; Fold-change: 0.941226017; Z-score: 1.524716868 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.18E-09; Fold-change: 1.221050703; Z-score: 1.553452398 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Adrenal cancer [ICD-11: 2D11]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Adrenal cortex | |
The Specific Disease | Adrenocortical carcinoma | |
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 8.38E-10; Fold-change: -0.624867122; Z-score: -1.861465491 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Head and neck cancer [ICD-11: 2D42]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Head and neck | |
The Specific Disease | Head and neck cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.55E-06; Fold-change: -0.30905338; Z-score: -0.478301965 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Pituitary cancer [ICD-11: 2F37]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Pituitary | |
The Specific Disease | Pituitary gonadotrope tumor | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.007538032; Fold-change: -0.715715128; Z-score: -1.060164094 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Pituitary | |
The Specific Disease | Pituitary cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.014375633; Fold-change: -0.523068992; Z-score: -0.959836389 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 03
Thrombocytopenia [ICD-11: 3B64]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Thrombocytopenia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.893032326; Fold-change: 0.180230002; Z-score: 0.182316253 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 04
Lupus erythematosus [ICD-11: 4A40]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Lupus erythematosus | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.36E-08; Fold-change: -0.18478003; Z-score: -0.556843473 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Autoimmune disease [ICD-11: 4A4Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral monocyte | |
The Specific Disease | Autoimmune uveitis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.126173523; Fold-change: -0.248729891; Z-score: -1.842830026 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 05
Hyperlipoproteinaemia [ICD-11: 5C80]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Familial hypercholesterolemia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.345885176; Fold-change: -0.145924601; Z-score: -0.80411335 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 06
Schizophrenia [ICD-11: 6A20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Superior temporal cortex | |
The Specific Disease | Schizophrenia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.519742084; Fold-change: 0.010582245; Z-score: 0.051290214 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 08
Multiple sclerosis [ICD-11: 8A40]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Spinal cord | |
The Specific Disease | Multiple sclerosis | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.492398664; Fold-change: 0.319199829; Z-score: 0.451446552 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Plasmacytoid dendritic cells | |
The Specific Disease | Multiple sclerosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.189661004; Fold-change: -0.039500048; Z-score: -0.133688723 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Epilepsy [ICD-11: 8A60]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peritumoral cortex | |
The Specific Disease | Epilepsy | |
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 0.680317325; Fold-change: 0.098217565; Z-score: 0.114922134 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Cerebral ischaemic stroke [ICD-11: 8B11]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Cardioembolic Stroke | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.103224854; Fold-change: 0.167249096; Z-score: 0.445048283 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Peripheral blood | |
The Specific Disease | Ischemic stroke | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.675937824; Fold-change: 0.013420906; Z-score: 0.062339758 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 1
HIV [ICD-11: 1C60-1C62]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | White matter | |
The Specific Disease | HIV | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.174486593; Fold-change: 0.127833336; Z-score: 0.460730352 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Influenza [ICD-11: 1E30]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Influenza | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.040041736; Fold-change: -0.235461001; Z-score: -1.703608832 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Chronic hepatitis C [ICD-11: 1E51.1]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Chronic hepatitis C | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.137745678; Fold-change: 0.15063636; Z-score: 1.352524474 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Sepsis [ICD-11: 1G40-1G41]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Sepsis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.053788063; Fold-change: -0.091980013; Z-score: -0.336944674 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Septic shock [ICD-11: 1G41]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Septic shock | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.98E-05; Fold-change: -0.132438223; Z-score: -0.489651837 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Pediatric respiratory syncytial virus infection [ICD-11: CA40.11]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Pediatric respiratory syncytial virus infection | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.131459839; Fold-change: -0.038678512; Z-score: -0.209505175 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 11
Essential hypertension [ICD-11: BA00]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Essential hypertension | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.49241841; Fold-change: 0.105195651; Z-score: 0.842746732 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Myocardial infarction [ICD-11: BA41]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Myocardial infarction | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.88776748; Fold-change: -0.07193114; Z-score: -0.143185041 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Coronary artery disease [ICD-11: BA8Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Coronary artery disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.090937894; Fold-change: -0.382159337; Z-score: -1.378264313 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Aortic stenosis [ICD-11: BB70]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Calcified aortic valve | |
The Specific Disease | Aortic stenosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.540841169; Fold-change: 0.038208094; Z-score: 0.112812081 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Arteriosclerosis [ICD-11: BD40]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Arteriosclerosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.620558298; Fold-change: 0.081722895; Z-score: 0.368450696 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Aneurysm [ICD-11: BD50]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Intracranial artery | |
The Specific Disease | Aneurysm | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.079022078; Fold-change: 0.446861501; Z-score: 0.521428737 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 12
Immunodeficiency [ICD-11: 4A00-4A20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Immunodeficiency | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.928017036; Fold-change: 0.027796359; Z-score: 0.244110809 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Apnea [ICD-11: 7A40]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Hyperplastic tonsil | |
The Specific Disease | Apnea | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.61331898; Fold-change: 0.710307621; Z-score: 1.010964659 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Olive pollen allergy [ICD-11: CA08.00]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Olive pollen allergy | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000130509; Fold-change: 0.253479212; Z-score: 5.454557001 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Chronic rhinosinusitis [ICD-11: CA0A]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Sinus mucosa | |
The Specific Disease | Chronic rhinosinusitis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.03613705; Fold-change: -1.239125643; Z-score: -1.488731846 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Chronic obstructive pulmonary disease [ICD-11: CA22]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Lung | |
The Specific Disease | Chronic obstructive pulmonary disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.945243734; Fold-change: 0.086894953; Z-score: 0.118982046 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Small airway epithelium | |
The Specific Disease | Chronic obstructive pulmonary disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.58E-06; Fold-change: -0.419476238; Z-score: -0.735740102 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Asthma [ICD-11: CA23]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Nasal and bronchial airway | |
The Specific Disease | Asthma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.046526521; Fold-change: 0.150900096; Z-score: 0.209637337 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Human rhinovirus infection [ICD-11: CA42]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Nasal Epithelium | |
The Specific Disease | Human rhinovirus infection | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.68012808; Fold-change: 0.047856298; Z-score: 0.117206122 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Idiopathic pulmonary fibrosis [ICD-11: CB03.4]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Lung | |
The Specific Disease | Idiopathic pulmonary fibrosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.90920054; Fold-change: 0.273977035; Z-score: 0.41854956 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 13
Periodontal disease [ICD-11: DA0C]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Gingival | |
The Specific Disease | Periodontal disease | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.059606034; Fold-change: 0.165082743; Z-score: 0.300694936 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Eosinophilic gastritis [ICD-11: DA42.2]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Gastric antrum | |
The Specific Disease | Eosinophilic gastritis | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.145214971; Fold-change: 0.686553886; Z-score: 1.825361698 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Liver failure [ICD-11: DB99.7-DB99.8]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Liver | |
The Specific Disease | Liver failure | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.513852363; Fold-change: -0.177259373; Z-score: -0.275767173 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Ulcerative colitis [ICD-11: DD71]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Colon mucosal | |
The Specific Disease | Ulcerative colitis | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.000790738; Fold-change: 0.644599356; Z-score: 1.07767921 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Irritable bowel syndrome [ICD-11: DD91.0]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Rectal colon | |
The Specific Disease | Irritable bowel syndrome | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.90282881; Fold-change: -0.052157386; Z-score: -0.134927141 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 14
Atopic dermatitis [ICD-11: EA80]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Atopic dermatitis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.40E-06; Fold-change: 0.328084157; Z-score: 1.293952441 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Psoriasis [ICD-11: EA90]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Psoriasis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.73E-19; Fold-change: 1.109824683; Z-score: 1.74998354 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.39E-15; Fold-change: 0.691827615; Z-score: 1.451054264 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Vitiligo [ICD-11: ED63.0]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Vitiligo | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.014055711; Fold-change: 0.486225322; Z-score: 1.548773304 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Alopecia [ICD-11: ED70]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin from scalp | |
The Specific Disease | Alopecia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.54E-08; Fold-change: -0.432371591; Z-score: -1.283643597 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Sensitive skin [ICD-11: EK0Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Sensitive skin | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.563278312; Fold-change: 0.084183742; Z-score: 0.622265826 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 15
Osteoarthritis [ICD-11: FA00-FA0Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Synovial | |
The Specific Disease | Osteoarthritis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.254373284; Fold-change: 0.846145529; Z-score: 0.675086614 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Arthropathy [ICD-11: FA00-FA5Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Arthropathy | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.875650061; Fold-change: -0.066182607; Z-score: -0.319861682 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Arthritis [ICD-11: FA20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Arthritis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.034285653; Fold-change: -0.087512265; Z-score: -0.272576429 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Rheumatoid arthritis [ICD-11: FA20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Synovial | |
The Specific Disease | Rheumatoid arthritis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.29E-05; Fold-change: 0.477190709; Z-score: 3.324250862 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Ankylosing spondylitis [ICD-11: FA92.0Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Pheripheral blood | |
The Specific Disease | Ankylosing spondylitis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.170445708; Fold-change: -0.118976136; Z-score: -1.129146188 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Osteoporosis [ICD-11: FB83]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bone marrow | |
The Specific Disease | Osteoporosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.156646718; Fold-change: 0.656431062; Z-score: 1.346923949 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 16
Endometriosis [ICD-11: GA10]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Endometrium | |
The Specific Disease | Endometriosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.31983757; Fold-change: -0.090333359; Z-score: -0.068687586 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Interstitial cystitis [ICD-11: GC00.3]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bladder | |
The Specific Disease | Interstitial cystitis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.01592439; Fold-change: 0.387827252; Z-score: 2.647741974 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 19
Preterm birth [ICD-11: KA21.4Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Myometrium | |
The Specific Disease | Preterm birth | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.618737094; Fold-change: -0.020715258; Z-score: -0.094760443 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 2
Acute myelocytic leukemia [ICD-11: 2A60]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bone marrow | |
The Specific Disease | Acute myelocytic leukemia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.565633955; Fold-change: -0.031647628; Z-score: -0.133761274 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Myeloma [ICD-11: 2A83]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bone marrow | |
The Specific Disease | Myeloma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.050305744; Fold-change: -0.171159989; Z-score: -0.746891587 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Peripheral blood | |
The Specific Disease | Myeloma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.795183884; Fold-change: -0.088178101; Z-score: -0.390222655 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Oral cancer [ICD-11: 2B6E]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Oral | |
The Specific Disease | Oral cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.009191058; Fold-change: -0.367225058; Z-score: -0.415387928 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.034160583; Fold-change: -0.322359422; Z-score: -0.372247226 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Esophagal cancer [ICD-11: 2B70]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Esophagus | |
The Specific Disease | Esophagal cancer | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.074065491; Fold-change: -0.6495318; Z-score: -0.796651072 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Rectal cancer [ICD-11: 2B92]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Rectal colon | |
The Specific Disease | Rectal cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.039083871; Fold-change: 0.950409173; Z-score: 1.522824476 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.026176519; Fold-change: 1.225592485; Z-score: 1.355429519 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Skin cancer [ICD-11: 2C30-2C3Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Skin cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.000561407; Fold-change: -0.134591362; Z-score: -0.250894013 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 4.79E-09; Fold-change: -0.451769846; Z-score: -0.866781137 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Renal cancer [ICD-11: 2C90-2C91]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Kidney | |
The Specific Disease | Renal cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.013914053; Fold-change: 0.334525856; Z-score: 0.619506522 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.47E-06; Fold-change: 0.546122592; Z-score: 0.795229668 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Ureter cancer [ICD-11: 2C92]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Urothelium | |
The Specific Disease | Ureter cancer | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.583487605; Fold-change: 0.126951359; Z-score: 0.132643336 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 20
Simpson golabi behmel syndrome [ICD-11: LD2C]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Adipose | |
The Specific Disease | Simpson golabi behmel syndrome | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.542208647; Fold-change: 0.045608909; Z-score: 0.172469454 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Tuberous sclerosis complex [ICD-11: LD2D.2]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Perituberal | |
The Specific Disease | Tuberous sclerosis complex | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.0272008; Fold-change: 0.528612626; Z-score: 2.967721336 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 3
Anemia [ICD-11: 3A00-3A9Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Bone marrow | |
The Specific Disease | Anemia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.36416184; Fold-change: -0.090632396; Z-score: -0.47996189 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Sickle cell disease [ICD-11: 3A51.0-3A51.3]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Sickle cell disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.456170533; Fold-change: 0.036006238; Z-score: 0.19276444 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Thrombocythemia [ICD-11: 3B63]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Thrombocythemia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.008659013; Fold-change: 0.167900782; Z-score: 1.080805558 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 4
Scleroderma [ICD-11: 4A42.Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Scleroderma | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.001694248; Fold-change: 0.474194121; Z-score: 1.815107486 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Sjogren syndrome [ICD-11: 4A43]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Salivary gland | |
The Specific Disease | Sjogren syndrome | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.568134001; Fold-change: -0.156406303; Z-score: -0.349419314 | |
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 0.003175368; Fold-change: -0.415437371; Z-score: -2.556168177 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Behcet disease [ICD-11: 4A62]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Peripheral blood | |
The Specific Disease | Behcet disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.594810134; Fold-change: -0.01297974; Z-score: -0.036829801 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Autosomal dominant monocytopenia [ICD-11: 4B04]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Autosomal dominant monocytopenia | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.113345465; Fold-change: -0.148853575; Z-score: -1.326135866 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 5
Type 2 diabetes [ICD-11: 5A11]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Liver | |
The Specific Disease | Type 2 diabetes | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.557427663; Fold-change: 0.015424073; Z-score: 0.067532206 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Polycystic ovary syndrome [ICD-11: 5A80.1]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Vastus lateralis muscle | |
The Specific Disease | Polycystic ovary syndrome | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.79914415; Fold-change: 0.098835265; Z-score: 0.542961465 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Obesity [ICD-11: 5B81]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Subcutaneous Adipose | |
The Specific Disease | Obesity | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.67601806; Fold-change: 0.133982608; Z-score: 0.374252154 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Pompe disease [ICD-11: 5C51.3]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Biceps muscle | |
The Specific Disease | Pompe disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.03074452; Fold-change: 0.652127453; Z-score: 1.532010415 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Batten disease [ICD-11: 5C56.1]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Batten disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.92937804; Fold-change: 0.030537859; Z-score: 0.110119713 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 6
Autism [ICD-11: 6A02]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Autism | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.177606044; Fold-change: -0.049143916; Z-score: -0.217712418 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Anxiety disorder [ICD-11: 6B00-6B0Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Anxiety disorder | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.684674824; Fold-change: -0.004961368; Z-score: -0.015952233 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
ICD Disease Classification 8
Parkinson disease [ICD-11: 8A00]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Substantia nigra | |
The Specific Disease | Parkinson disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.769728607; Fold-change: -0.035323157; Z-score: -0.11285505 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Huntington disease [ICD-11: 8A01]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Huntington disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.998664923; Fold-change: 0.03228522; Z-score: 0.169380183 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Alzheimer disease [ICD-11: 8A20]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Entorhinal cortex | |
The Specific Disease | Alzheimer disease | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.54E-06; Fold-change: 0.18033988; Z-score: 0.641130722 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Seizure [ICD-11: 8A60-8A6Z]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Whole blood | |
The Specific Disease | Seizure | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.571354224; Fold-change: 0.011334196; Z-score: 0.043421958 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Lateral sclerosis [ICD-11: 8B60.4]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Skin | |
The Specific Disease | Lateral sclerosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.251657193; Fold-change: 0.393302035; Z-score: 0.95853088 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
The Studied Tissue | Cervical spinal cord | |
The Specific Disease | Lateral sclerosis | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.218138048; Fold-change: 0.143522258; Z-score: 0.330797415 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Muscular atrophy [ICD-11: 8C70]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Muscle | |
The Specific Disease | Muscular atrophy | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.05684851; Fold-change: 0.123851789; Z-score: 0.310650266 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
Myopathy [ICD-11: 8C70.6]
Differential expression pattern of antigen in diseases | ||
The Studied Tissue | Muscle | |
The Specific Disease | Myopathy | |
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 0.734562509; Fold-change: -0.03418859; Z-score: -0.262871323 | |
Disease-specific Antigen Abundances | Click to View the Clearer Original Diagram | |
References
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