Antigen ID	TAR0GAQGW
Antigen Name	Ly6/PLAUR domain-containing protein 3 (LYPD3)
Gene Name	LYPD3
Gene ID	27076
Synonym	C4.4A; UNQ491; PRO1007; GPI-anchored metastasis-associated protein C4.4A homolog;Matrigel-induced gene C4 protein
Sequence	MDPARKAGAQAMIWTAGWLLLLLLRGGAQALECYSCVQKADDGCSPNKMKTVKCAPGVDV CTEAVGAVETIHGQFSLAVRGCGSGLPGKNDRGLDLHGLLAFIQLQQCAQDRCNAKLNLT SRALDPAGNESAYPPNGVECYSCVGLSREACQGTSPPVVSCYNASDHVYKGCFDGNVTLT AANVTVSLPVRGCVQDEFCTRDGVTGPGFTLSGSCCQGSRCNSDLRNKTYFSPRIPPLVR LPPPEPTTVASTTSVTTSTSAPVRPTSTTKPMPAPTSQTPRQGVEHEASRDEEPRLTGGA AGHQDRSNSGQYPAKGGPQQPHNKGCVAPTAGLAALLLAVAAGVLL     Click to Show/Hide
Function	Supports cell migration. May be involved in urothelial cell- matrix interactions. May be involved in tumor progression.     Click to Show/Hide
Uniprot Entry	LYPD3_HUMAN
HGNC ID	HGNC:24880
KEGG ID	hsa:27076

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	C4.4A-EC3	NAMPT inhibitor 4	Nicotinamide phosphoribosyltransferase (NAMPT)	Mc-Val-Ala	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	C4.4A-EC4	NAMPT inhibitor 5	Nicotinamide phosphoribosyltransferase (NAMPT)	Open-chain glycine maleimide	[1]
ADC Info	C4.4A-EC5	NAMPT inhibitor 6	Nicotinamide phosphoribosyltransferase (NAMPT)	Open-chain glycine maleimide-PEG	[2]
ADC Info	C4.4A-EC2	NAMPT inhibitor 6	Nicotinamide phosphoribosyltransferase (NAMPT)	Maleimido-caproyl	[1]
ADC Info	C4.4A-EC1	NAMPT inhibitor 4	Nicotinamide phosphoribosyltransferase (NAMPT)	Maleimido-caproyl	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	Lupartumab amadotin	Undisclosed	Undisclosed	Undisclosed	[3]

Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Bacterial infection of gingival
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 7.57E-19; Fold-change: -0.390192899; Z-score: -1.780038625
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Differential expression pattern of antigen in diseases
The Studied Tissue	Brainstem
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.623070178; Fold-change: 0.047086941; Z-score: 0.845660389
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The Studied Tissue	White matter
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.121883293; Fold-change: -0.179990754; Z-score: -0.559230713
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The Studied Tissue	Brainstem
The Specific Disease	Neuroectodermal tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000260472; Fold-change: -0.915550872; Z-score: -1.939009974
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The Studied Tissue	Nervous
The Specific Disease	Brain cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.041423848; Fold-change: -0.061626058; Z-score: -0.154671308
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Polycythemia vera
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.52E-08; Fold-change: 0.129693015; Z-score: 0.879599718
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The Studied Tissue	Whole blood
The Specific Disease	Myelofibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.017322993; Fold-change: 0.09457585; Z-score: 0.662207975
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myelodysplastic syndromes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.118800343; Fold-change: -0.112104398; Z-score: -0.360215863
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.047567642; Fold-change: -2.633893151; Z-score: -2.079841739
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Tonsil
The Specific Disease	Lymphoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.395267101; Fold-change: -0.080338728; Z-score: -0.310492774
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric
The Specific Disease	Gastric cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.602527337; Fold-change: 0.018410876; Z-score: 0.056838372
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 6.10E-06; Fold-change: 0.24831296; Z-score: 0.788911873
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon
The Specific Disease	Colon cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 7.35E-11; Fold-change: 0.111767682; Z-score: 0.414982687
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.002643121; Fold-change: 0.029558709; Z-score: 0.098846898
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pancreas
The Specific Disease	Pancreatic cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.032205491; Fold-change: 0.09564025; Z-score: 0.281345305
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.000852422; Fold-change: 0.06584446; Z-score: 0.137519475
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.247754976; Fold-change: -0.037886313; Z-score: -0.209453366
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.336427733; Fold-change: -0.041058577; Z-score: -0.177221767
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.067395176; Fold-change: 0.382216173; Z-score: 1.37262803
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Lung cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.48E-99; Fold-change: 0.666480385; Z-score: 2.056229821
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.14E-66; Fold-change: 0.533749526; Z-score: 1.582820203
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Melanoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.04556955; Fold-change: -1.342447973; Z-score: -0.635883062
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Sarcoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.55E-05; Fold-change: 0.06865416; Z-score: 0.212594852
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.547062767; Fold-change: -0.112337492; Z-score: -0.326004674
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Breast
The Specific Disease	Breast cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.001570793; Fold-change: 0.03797971; Z-score: 0.039497238
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.0002227; Fold-change: 0.281471489; Z-score: 0.30662488
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Ovarian
The Specific Disease	Ovarian cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.515655088; Fold-change: -0.172841942; Z-score: -0.217512893
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.83E-05; Fold-change: 0.417169662; Z-score: 1.154184247
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Cervical
The Specific Disease	Cervical cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.19E-06; Fold-change: -0.894977558; Z-score: -1.40377446
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Uterine cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.105466618; Fold-change: 0.278189253; Z-score: 0.130558189
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.27E-07; Fold-change: 1.040673199; Z-score: 3.336005302
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Differential expression pattern of antigen in diseases
The Studied Tissue	Prostate
The Specific Disease	Prostate cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.942931032; Fold-change: -0.113611533; Z-score: -0.117804486
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Bladder cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.030372481; Fold-change: 0.933168885; Z-score: 1.114590201
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Differential expression pattern of antigen in diseases
The Studied Tissue	Uvea
The Specific Disease	Retinoblastoma tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.016686143; Fold-change: -0.267058622; Z-score: -1.284876097
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Differential expression pattern of antigen in diseases
The Studied Tissue	Thyroid
The Specific Disease	Thyroid cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 8.50E-06; Fold-change: 0.109387507; Z-score: 0.328161246
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 6.32E-05; Fold-change: 0.169846813; Z-score: 0.550178204
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adrenal cortex
The Specific Disease	Adrenocortical carcinoma
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 9.36E-07; Fold-change: -0.803669791; Z-score: -1.635739749
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Differential expression pattern of antigen in diseases
The Studied Tissue	Head and neck
The Specific Disease	Head and neck cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.52E-05; Fold-change: -0.01435805; Z-score: -0.005630348
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pituitary
The Specific Disease	Pituitary gonadotrope tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.96761151; Fold-change: -0.022148051; Z-score: -0.077475101
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The Studied Tissue	Pituitary
The Specific Disease	Pituitary cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.489850515; Fold-change: 0.14767973; Z-score: 0.390437274
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.604865048; Fold-change: 0.728489811; Z-score: 0.694771724
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Lupus erythematosus
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.108797725; Fold-change: -0.209521499; Z-score: -0.386947536
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral monocyte
The Specific Disease	Autoimmune uveitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.009690717; Fold-change: -0.686044045; Z-score: -1.566802718
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Familial hypercholesterolemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.00248489; Fold-change: -0.53901715; Z-score: -1.468259921
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Differential expression pattern of antigen in diseases
The Studied Tissue	Superior temporal cortex
The Specific Disease	Schizophrenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.254884608; Fold-change: -0.064279935; Z-score: -0.441336553
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Differential expression pattern of antigen in diseases
The Studied Tissue	Spinal cord
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.687417772; Fold-change: -0.028972753; Z-score: -0.186337147
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The Studied Tissue	Plasmacytoid dendritic cells
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.882297288; Fold-change: -0.110954738; Z-score: -0.415472033
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peritumoral cortex
The Specific Disease	Epilepsy
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.226644113; Fold-change: 0.153701089; Z-score: 2.198220695
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Cardioembolic Stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.894439352; Fold-change: -0.041379369; Z-score: -0.185557052
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The Studied Tissue	Peripheral blood
The Specific Disease	Ischemic stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.260556497; Fold-change: 0.459691456; Z-score: 0.59387213
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Differential expression pattern of antigen in diseases
The Studied Tissue	White matter
The Specific Disease	HIV
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.111371441; Fold-change: -0.118472868; Z-score: -0.49591031
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Influenza
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.590848056; Fold-change: 0.613625115; Z-score: 0.815011422
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Chronic hepatitis C
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.184772531; Fold-change: 0.288000229; Z-score: 0.566499236
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Sepsis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.013009962; Fold-change: -0.157481967; Z-score: -0.380054982
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Septic shock
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.404207999; Fold-change: 0.007517856; Z-score: 0.032967684
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Pediatric respiratory syncytial virus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.109715258; Fold-change: -0.132940064; Z-score: -0.329130847
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Essential hypertension
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.553105628; Fold-change: 0.094712621; Z-score: 1.187458531
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Myocardial infarction
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.349354583; Fold-change: 0.118197965; Z-score: 0.204022023
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Coronary artery disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.465145208; Fold-change: -0.071212036; Z-score: -0.056287476
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Differential expression pattern of antigen in diseases
The Studied Tissue	Calcified aortic valve
The Specific Disease	Aortic stenosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.717766204; Fold-change: 0.031422978; Z-score: 0.059866789
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arteriosclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.526363845; Fold-change: -0.116611271; Z-score: -0.677482638
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Differential expression pattern of antigen in diseases
The Studied Tissue	Intracranial artery
The Specific Disease	Aneurysm
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.011383414; Fold-change: -0.203227422; Z-score: -0.814939133
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Immunodeficiency
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.392005819; Fold-change: -0.049061541; Z-score: -0.534846197
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Differential expression pattern of antigen in diseases
The Studied Tissue	Hyperplastic tonsil
The Specific Disease	Apnea
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.323030073; Fold-change: -0.147158951; Z-score: -0.274932527
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Olive pollen allergy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.992049086; Fold-change: 0.085011233; Z-score: 0.152422986
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Differential expression pattern of antigen in diseases
The Studied Tissue	Sinus mucosa
The Specific Disease	Chronic rhinosinusitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.173520328; Fold-change: 0.142705826; Z-score: 0.842069884
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.822928983; Fold-change: 0.020969614; Z-score: 0.06931746
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The Studied Tissue	Small airway epithelium
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.150187264; Fold-change: 0.059925662; Z-score: 0.093673955
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal and bronchial airway
The Specific Disease	Asthma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.12E-07; Fold-change: 1.03203894; Z-score: 0.67912225
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal Epithelium
The Specific Disease	Human rhinovirus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.767389491; Fold-change: 0.055517791; Z-score: 0.055244657
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Idiopathic pulmonary fibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.110465986; Fold-change: 0.116867384; Z-score: 0.546063641
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Periodontal disease
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.24E-16; Fold-change: -0.356320814; Z-score: -1.647469605
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric antrum
The Specific Disease	Eosinophilic gastritis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.756135776; Fold-change: -0.009061946; Z-score: -0.029142551
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver failure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000187139; Fold-change: 0.284291671; Z-score: 2.300092878
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon mucosal
The Specific Disease	Ulcerative colitis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.343167592; Fold-change: -0.128310959; Z-score: -0.396259067
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Irritable bowel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.779077777; Fold-change: -0.09909961; Z-score: -0.444840467
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Atopic dermatitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 9.23E-05; Fold-change: -0.710821441; Z-score: -3.696341083
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Psoriasis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.32E-21; Fold-change: 0.489254346; Z-score: 1.357325159
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.08E-09; Fold-change: 0.341467854; Z-score: 0.614506189
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Vitiligo
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.592696595; Fold-change: -0.025186026; Z-score: -0.158475724
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin from scalp
The Specific Disease	Alopecia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000472815; Fold-change: -0.067660141; Z-score: -0.507209014
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Sensitive skin
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.211153672; Fold-change: 0.178096738; Z-score: 0.553388505
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Osteoarthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.983898504; Fold-change: 0.017087375; Z-score: 0.060010497
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthropathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.623938784; Fold-change: -0.049806495; Z-score: -0.293396172
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.181042091; Fold-change: -0.136563991; Z-score: -0.507240443
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Rheumatoid arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.076891348; Fold-change: -0.081187596; Z-score: -0.277123135
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pheripheral blood
The Specific Disease	Ankylosing spondylitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.797155004; Fold-change: -0.021717943; Z-score: -0.077733343
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Osteoporosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.111027495; Fold-change: 0.170166995; Z-score: 1.108435329
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Endometriosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000285253; Fold-change: 0.356296144; Z-score: 0.894054075
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Interstitial cystitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.003015999; Fold-change: -2.056453137; Z-score: -2.81370264
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Myometrium
The Specific Disease	Preterm birth
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.910936253; Fold-change: -0.17825776; Z-score: -0.451766715
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Acute myelocytic leukemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 4.95E-12; Fold-change: -0.258498053; Z-score: -0.598759907
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.61E-06; Fold-change: -0.734117941; Z-score: -3.817032975
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Peripheral blood
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.933381742; Fold-change: -0.020686535; Z-score: -0.112724663
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Oral
The Specific Disease	Oral cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.042892602; Fold-change: -0.628358978; Z-score: -0.48698385
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.46E-10; Fold-change: -1.170113048; Z-score: -0.95404911
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Esophagus
The Specific Disease	Esophagal cancer
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.007310867; Fold-change: -1.974688918; Z-score: -1.999062071
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Rectal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.003827256; Fold-change: 0.208018678; Z-score: 1.409909585
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.001523505; Fold-change: 0.274107041; Z-score: 1.499246089
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Skin cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.30E-74; Fold-change: -2.633957769; Z-score: -5.581189411
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 5.66E-63; Fold-change: -2.542062543; Z-score: -3.718803135
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Kidney
The Specific Disease	Renal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.008262953; Fold-change: -0.459469153; Z-score: -0.977888322
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 8.63E-13; Fold-change: -0.684279889; Z-score: -1.511180451
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Urothelium
The Specific Disease	Ureter cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.175920898; Fold-change: -0.082591918; Z-score: -0.07798167
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adipose
The Specific Disease	Simpson golabi behmel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.100773081; Fold-change: 0.018739188; Z-score: 0.235717865
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Differential expression pattern of antigen in diseases
The Studied Tissue	Perituberal
The Specific Disease	Tuberous sclerosis complex
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.040477473; Fold-change: 0.260559901; Z-score: 1.557729836
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Anemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.018332642; Fold-change: 0.610329919; Z-score: 1.480824407
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Sickle cell disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.23904737; Fold-change: -0.163039848; Z-score: -0.574895781
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocythemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.004776192; Fold-change: 0.161555238; Z-score: 1.159411502
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Scleroderma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.748184025; Fold-change: -0.014907769; Z-score: -0.087028526
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Differential expression pattern of antigen in diseases
The Studied Tissue	Salivary gland
The Specific Disease	Sjogren syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.663746454; Fold-change: 0.030216076; Z-score: 0.161488283
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.19E-05; Fold-change: -0.723705543; Z-score: -8.578286748
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Behcet disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.474602291; Fold-change: 0.03942598; Z-score: 0.128783643
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autosomal dominant monocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.260939337; Fold-change: -0.085388849; Z-score: -0.165251191
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Type 2 diabetes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.777924904; Fold-change: 0.012341725; Z-score: 0.091193616
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Differential expression pattern of antigen in diseases
The Studied Tissue	Vastus lateralis muscle
The Specific Disease	Polycystic ovary syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.099851651; Fold-change: -0.029210495; Z-score: -0.218473368
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Differential expression pattern of antigen in diseases
The Studied Tissue	Subcutaneous Adipose
The Specific Disease	Obesity
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.679881031; Fold-change: 0.036948428; Z-score: 0.198637868
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Differential expression pattern of antigen in diseases
The Studied Tissue	Biceps muscle
The Specific Disease	Pompe disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.294620661; Fold-change: -0.047723261; Z-score: -0.297039198
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Batten disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.370842014; Fold-change: 0.110135381; Z-score: 0.799011456
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autism
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.1706593; Fold-change: -0.10501759; Z-score: -0.495329952
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Anxiety disorder
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.918074312; Fold-change: -0.024431664; Z-score: -0.078389132
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Substantia nigra
The Specific Disease	Parkinson disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.783689284; Fold-change: 0.056863507; Z-score: 0.177589285
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Huntington disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.191789771; Fold-change: -0.06597179; Z-score: -0.227511892
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Entorhinal cortex
The Specific Disease	Alzheimer disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.455682896; Fold-change: -0.028189456; Z-score: -0.161084465
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Seizure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.62622378; Fold-change: -0.033164837; Z-score: -0.141714326
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.090015677; Fold-change: 0.156995946; Z-score: 1.378338355
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Cervical spinal cord
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.569055736; Fold-change: 0.135087984; Z-score: 0.522386586
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Muscular atrophy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.241955658; Fold-change: 0.022388872; Z-score: 0.123217014
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Myopathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.119461639; Fold-change: -0.211531908; Z-score: -1.045343425
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Ref 1	A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug Chem. 2022 Jun 15;33(6):1210-1221.
Ref 2	Taxol(r) structure-activity-relationships - synthesis and biological evaluation of taxol analogs modified at c-7. Bioorg Med Chem Lett. 1994;4(18):2223-2228.
Ref 3	Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer. Mol Cancer Ther. 2017 May;16(5):893-904. doi: 10.1158/1535-7163.MCT-16-0474. Epub 2017 Mar 14.