Antigen Information
General Information of This Antigen
| Antigen ID | TAR0FZYGA |
|||||
|---|---|---|---|---|---|---|
| Antigen Name | C-type lectin domain family 12 member A (CLEC12A) |
|||||
| Gene Name | CLEC12A |
|||||
| Gene ID | ||||||
| Synonym | CLL1; DCAL2; MICL; C-type lectin-like molecule 1;Dendritic cell-associated lectin 2;Myeloid inhibitory C-type lectin-like receptor;CD_antigen=CD371 |
|||||
| Sequence |
MSEEVTYADLQFQNSSEMEKIPEIGKFGEKAPPAPSHVWRPAALFLTLLCLLLLIGLGVL
ASMFHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRE LYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFI KSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHC TYKKRMICEKMANPVQLGSTYFREA Click to Show/Hide
|
|||||
| Function |
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of .get MAP kinases.
Click to Show/Hide
|
|||||
| Uniprot Entry | ||||||
| HGNC ID | ||||||
| KEGG ID | ||||||
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
6E7.N54A LC K149C
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
CN106714844B ADC-117 |
PNU-159682 |
DNA topoisomerase 2-alpha (TOP2A) |
Undisclosed |
[1] | |
CN106714844B ADC-118 |
PNU-159682 |
DNA topoisomerase 2-alpha (TOP2A) |
Undisclosed |
[1] | |
CN106714844B ADC-133 |
PNU-159682 |
DNA topoisomerase 2-alpha (TOP2A) |
Undisclosed |
[1] |
Anti-CLL-1 THIOMAB Anti-ody
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
Anti-CLL-1-ds-PBD |
SG2000 |
Human Deoxyribonucleic acid (hDNA) |
Undisclosed |
[2] |
Fully humanized Anti-CLL1 mAb
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
CLL1-ADC |
D211 |
Human Deoxyribonucleic acid (hDNA) |
Mal-PEG8-Val-Cit-PABC |
[3] |
MCLL0517A
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
IGAC-90 |
IG-L-18 Payload |
Undisclosed |
IG-L-25 linker |
[4] |
References