Antigen Information
General Information of This Antigen (ID: TAR0EHHCN)
| Antigen Name | T-cell surface glycoprotein CD5 (CD5) |
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|---|---|---|---|---|---|---|
| Gene Name | CD5 |
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| Gene ID | ||||||
| Synonym | LEU1; Lymphocyte antigen T1/Leu-1;CD5 |
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| Sequence |
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD NSSDSDYDLHGAQRL Click to Show/Hide
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| Function |
May act as a receptor in regulating T-cell proliferation.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Anti-CD5 mAb T101
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Telimomab aritox
[1]
|
Ricin A-chain |
Ribosome (RB) |
Undisclosed |
CD5 5D7 D265C/H435A
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
CD5 5D7 D265C/H435A ADC A
[2]
|
Amaninamide (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Mc-Val-Ala-PABC |
|
|
CD5 5D7 D265C/H435A ADC C
[2]
|
Alpha-amanitin (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Maleimido-caproyl |
References