Antigen Information
General Information of This Antigen
| Antigen ID | TAR0EHHCN |
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|---|---|---|---|---|---|---|
| Antigen Name | T-cell surface glycoprotein CD5 (CD5) |
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| Gene Name | CD5 |
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| Gene ID | ||||||
| Synonym | LEU1; Lymphocyte antigen T1/Leu-1;CD_antigen=CD5 |
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| Sequence |
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD NSSDSDYDLHGAQRL Click to Show/Hide
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| Function |
May act as a receptor in regulating T-cell proliferation.
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Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-CD5 mAb T101
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
Telimomab aritox |
Ricin A-chain |
Ribosome (RB) |
Undisclosed |
[1] |
CD5 5D7 D265C/H435A
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
CD5 5D7 D265C/H435A ADC A |
Amaninamide (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Mc-Val-Ala-PABC |
[2] | |
CD5 5D7 D265C/H435A ADC C |
Alpha-amanitin (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Maleimido-caproyl |
[2] |
References