LYLIN000127
     RDKit          3D

149152  0  0  1  0  0  0  0  0999 V2000
    4.7133   -2.8865    4.8594 C   0  0  0  0  0  2  0  0  0  0  0  0
    4.5591   -1.3619    3.2911 C   0  0  0  0  0  2  0  0  0  0  0  0
    5.1360    0.7617   -1.4294 C   0  0  0  0  0  2  0  0  0  0  0  0
    3.7758    2.0250   -2.5440 C   0  0  0  0  0  2  0  0  0  0  0  0
    4.0998   -4.2542    5.2514 C   0  0  0  0  0  2  0  0  0  0  0  0
    4.3174   -0.9504    1.8751 C   0  0  0  0  0  2  0  0  0  0  0  0
    4.6694   -0.1882   -0.2366 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.2552    1.9825   -2.3932 C   0  0  0  0  0  2  0  0  0  0  0  0
   -0.6246    2.8530   -4.4493 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7146    2.6799   -4.2997 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1981    3.2633   -5.6306 C   0  0  0  0  0  3  0  0  0  0  0  0
    1.8906    2.7052   -5.2025 C   0  0  0  0  0  2  0  0  0  0  0  0
   -0.4155    3.5706   -6.8270 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.6837    2.9174   -6.4819 C   0  0  0  0  0  2  0  0  0  0  0  0
    0.7700    3.7901   -7.7510 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.3216    3.4717   -7.7985 C   0  0  0  0  0  2  0  0  0  0  0  0
    5.2135   -1.7051    4.4061 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.0027    1.6374   -2.5007 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3197    1.9190   -2.5260 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2111    2.1537   -3.5298 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.1979   -5.0901    6.0929 N   0  0  0  0  0  1  0  0  0  0  0  0
    0.9168    2.1275   -2.9649 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.8348   -0.2609    0.8475 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5101   -6.2910    0.8637 C   0  0  0  0  0  1  0  0  0  0  0  0
   -1.6225   -4.8659    3.0280 C   0  0  0  0  0  1  0  0  0  0  0  0
    3.7541   -1.1744   -6.6037 C   0  0  0  0  0  2  0  0  0  0  0  0
    5.1186   -0.6109   -8.4555 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6177    1.7212   -9.0536 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.2100   -2.5542   -5.2162 C   0  0  0  0  0  3  0  0  0  0  0  0
   -0.6167   -5.8125    2.0647 C   0  0  0  0  0  3  0  0  0  0  0  0
    1.8755   -3.1761   -3.9955 C   0  0  0  0  0  3  0  0  0  0  0  0
    3.3852   -1.7888   -5.3235 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1716    3.1241   -9.5679 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5921   -7.0073    4.7480 C   0  0  0  0  0  0  0  0  0  0  0  0
   -7.9056   -1.5555    0.9732 C   0  0  0  0  0  2  0  0  0  0  0  0
   -6.0344   -2.8099    1.2301 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.7252   -7.1313    2.9589 C   0  0  0  0  0  2  0  0  0  0  0  0
    0.4520   -6.6750    2.7373 C   0  0  0  0  0  3  0  0  0  0  0  0
    2.9798   -4.0079   -0.5985 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6683   -3.1358   -2.8347 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.1439   -1.7251   -4.1404 C   0  0  0  0  0  3  0  0  0  0  0  0
   -2.1611   -7.3761    4.7762 C   0  0  0  0  0  3  0  0  0  0  0  0
  -10.5854    0.8648   -0.3243 C   0  0  0  0  0  0  0  0  0  0  0  0
   -9.1336   -1.0048    0.2301 C   0  0  0  0  0  2  0  0  0  0  0  0
   -5.0371   -3.9825    1.0363 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.6834   -5.9224    1.8321 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.1402   -8.1249    3.9966 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6796   -6.8950    1.8113 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1441   -4.6111    0.6788 C   0  0  0  0  0  3  0  0  0  0  0  0
    3.8369   -2.3933   -2.9271 C   0  0  0  0  0  3  0  0  0  0  0  0
   -2.8768   -6.9133    6.0225 C   0  0  0  0  0  2  0  0  0  0  0  0
    1.5038   -3.6177    1.5379 C   0  0  0  0  0  2  0  0  0  0  0  0
   -9.8031    1.1301   -1.5263 C   0  0  0  0  0  2  0  0  0  0  0  0
   -8.4572    0.7859   -2.3318 C   0  0  0  0  0  2  0  0  0  0  0  0
   -2.9078   -6.6510    7.5319 C   0  0  0  0  0  2  0  0  0  0  0  0
    0.8597   -2.7341    2.6331 C   0  0  0  0  0  2  0  0  0  0  0  0
   -2.8493   -6.8138    9.0877 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2547   -1.9274    3.9755 C   0  0  0  0  0  2  0  0  0  0  0  0
   -1.9425   -1.7212    4.8448 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.3242    1.4705   -2.4597 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.7547    2.8261   -4.3903 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3176    2.5007   -2.0574 C   0  0  0  0  0  3  0  0  0  0  0  0
   -3.4921    3.0237   -5.0475 C   0  0  0  0  0  2  0  0  0  0  0  0
   -5.4223    2.8904   -0.5671 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.8820    3.3431    1.5942 C   0  0  0  0  0  2  0  0  0  0  0  0
   -4.1445    3.9691    2.8197 C   0  0  0  0  0  2  0  0  0  0  0  0
   -3.4389    4.5680    3.9714 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3960    6.1216    5.5123 C   0  0  0  0  0  2  0  0  0  0  0  0
    1.5412    7.0655    5.0028 C   0  0  0  0  0  2  0  0  0  0  0  0
    5.3204    5.9926    2.6463 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.4174    7.4435    3.6094 C   0  0  0  0  0  2  0  0  0  0  0  0
    4.2940    7.0586    2.8245 C   0  0  0  0  0  2  0  0  0  0  0  0
    6.3307    4.9237    3.0810 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6996    5.9549    4.7980 C   0  0  0  0  0  2  0  0  0  0  0  0
    5.1495   -1.7344   -8.9542 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.9666    4.1260   -9.3577 O   0  0  0  0  0  1  0  0  0  0  0  0
   -0.1042   -6.3450    5.6894 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1947   -3.7323   -0.4650 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1882   -0.2519   -7.4750 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.1100    0.2987   -8.6413 N   0  0  0  0  0  2  0  0  0  0  0  0
  -10.3779   -0.1051    0.5116 N   0  0  0  0  0  2  0  0  0  0  0  0
    2.1310   -6.0326    0.8370 N   0  0  0  0  0  2  0  0  0  0  0  0
   -2.7949   -8.1713    3.8460 N   0  0  0  0  0  2  0  0  0  0  0  0
  -11.5214    1.6697   -0.1157 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2879   -5.0662    0.9079 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1108    3.1025  -10.3506 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1151   -7.6229    3.7510 N   0  0  0  0  0  2  0  0  0  0  0  0
   -7.0665   -2.1789    1.8756 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2490   -3.8422   -1.7766 N   0  0  0  0  0  2  0  0  0  0  0  0
   -4.9560   -8.7895    4.6789 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3182   -7.9725    2.0084 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8407   -1.8350    5.7295 O   0  0  0  0  0  0  0  0  0  0  0  0
   -7.2601    0.5872   -2.8686 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4930   -5.8202    9.8812 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0724   -7.9964    9.5017 O   0  0  0  0  0  1  0  0  0  0  0  0
   -5.6660    2.3136   -5.0869 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6193   -1.4942    5.1317 N   0  0  0  0  0  2  0  0  0  0  0  0
   -2.4678   -1.3393    3.5468 N   0  0  0  0  0  1  0  0  0  0  0  0
   -2.4921    2.7831   -5.8597 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8055    3.3145   -3.1219 N   0  0  0  0  0  2  0  0  0  0  0  0
   -5.8519    2.9999    0.7547 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3754    3.8758    5.0392 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8489    4.1176    4.0555 N   0  0  0  0  0  2  0  0  0  0  0  0
   -2.7480    5.7466    3.7751 N   0  0  0  0  0  2  0  0  0  0  0  0
    3.2412    7.9174    2.7299 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.7183    6.7139    5.9647 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.5067    4.8308    2.6066 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2038   -3.3173   -3.2291 C   0  0  0  0  0  3  0  0  0  0  0  0
   -2.0919   -3.9396   -0.9788 C   0  0  0  0  0  3  0  0  0  0  0  0
    5.0827    3.0338    3.3897 C   0  0  0  0  0  3  0  0  0  0  0  0
   -1.2308    1.3911    0.4264 C   0  0  0  0  0  3  0  0  0  0  0  0
   -2.4270   -1.9782   -2.8238 C   0  0  0  0  0  3  0  0  0  0  0  0
   -1.2720   -7.9151   -3.6660 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0190   -8.2362   -5.9145 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0745    1.5781    1.0356 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7479    2.6442    1.8810 C   0  0  0  0  0  3  0  0  0  0  0  0
    8.4640    0.3006    2.5039 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8523    5.8322   -0.3311 C   0  0  0  0  0  2  0  0  0  0  0  0
   -1.9809   -4.3664   -2.3376 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6251   -5.6855   -2.8092 C   0  0  0  0  0  2  0  0  0  0  0  0
   -2.1567    4.3815   -0.1025 C   0  0  0  0  0  2  0  0  0  0  0  0
    2.1672    4.7360    0.1030 C   0  0  0  0  0  1  0  0  0  0  0  0
    1.2745    3.9874    1.3431 C   0  0  0  0  0  3  0  0  0  0  0  0
   -2.2579    0.3398    0.0604 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5388    2.8321    0.1687 C   0  0  0  0  0  2  0  0  0  0  0  0
    3.5683    3.2953    3.1726 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3778   -1.6193   -1.4264 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.0973    1.0662    2.6472 C   0  0  0  0  0  2  0  0  0  0  0  0
   -2.1688   -2.6226   -0.5404 C   0  0  0  0  0  3  0  0  0  0  0  0
   -4.7273    7.2702   -0.0036 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8656   -8.5191   -4.9130 C   0  0  0  0  0  2  0  0  0  0  0  0
    0.6514    5.1577    2.1963 C   0  0  0  0  0  1  0  0  0  0  0  0
    5.8979    1.9475    3.0551 C   0  0  0  0  0  2  0  0  0  0  0  0
    3.1624   -8.5421   -5.4725 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7682   -6.7339   -3.0110 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0921    2.5312    2.2013 N   0  0  0  0  0  2  0  0  0  0  0  0
    2.9663    4.0003    3.9581 O   0  0  0  0  0  0  0  0  0  0  0  0
    8.9832   -0.1606    3.5704 O   0  0  0  0  0  1  0  0  0  0  0  0
   -3.4272    7.2283   -0.2770 N   0  0  0  0  0  2  0  0  0  0  0  0
    9.0791    0.2561    1.3712 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8952   -0.4319   -1.0400 N   0  0  0  0  0  2  0  0  0  0  0  0
    1.7039    1.0144    0.1588 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6384    6.0922   -0.2985 N   0  0  0  0  0  1  0  0  0  0  0  0
    1.7792   -7.9053   -7.1522 O   0  0  0  0  0  1  0  0  0  0  0  0
   -2.4631   -8.2676   -3.6074 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4230    0.4190    0.5346 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3155   -8.8755   -3.9310 N   0  0  0  0  0  2  0  0  0  0  0  0
   -5.3413    8.2682    0.4604 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1881    1.1101    1.3232 N   0  0  0  0  0  2  0  0  0  0  0  0
  1  5  1  0
  1 17  1  0
  2  6  1  0
  2 17  1  0
  3  7  1  0
  3 18  1  0
  4  8  1  0
  4 18  1  0
  5 21  1  0
  6 23  1  0
  7 23  1  0
  8 22  1  0
  9 10  2  0
  9 11  1  0
  9 20  1  0
 10 12  1  0
 10 22  1  0
 11 13  1  0
 11 99  1  0
 12 14  1  0
 13 15  1  0
 14 16  1  0
 15 16  1  0
 19 20  2  0
 19 22  1  0
 24 30  1  0
 25 30  1  0
 26 32  1  0
 26 79  1  0
 27 75  2  0
 27 79  1  0
 27 80  1  0
 28 33  1  0
 28 80  1  0
 29 31  2  0
 29 32  1  0
 31 40  1  0
 32 41  2  0
 33 76  1  0
 33 86  2  0
 34 42  1  0
 34 77  2  0
 34 87  1  0
 35 44  1  0
 35 88  1  0
 36 45  1  0
 36 88  1  0
 37 46  1  0
 37 47  1  0
 38 30  1  0
 38 48  1  0
 38 87  1  0
 39 49  1  0
 39 78  2  0
 39 89  1  0
 40 50  2  0
 40 89  1  0
 41 50  1  0
 42 51  1  0
 42 83  1  0
 43 53  1  0
 43 81  1  0
 43 84  2  0
 44 81  1  0
 45 85  1  0
 46 85  1  0
 47 83  1  0
 47 90  2  0
 48 82  1  0
 48 91  2  0
 49 52  1  0
 49 82  1  0
 51 55  1  0
 52 56  1  0
 53 54  1  0
 54 93  1  0
 55 57  1  0
 56 58  1  0
 57 94  2  0
 57 95  1  0
 58 97  1  0
 59 92  2  0
 59 97  1  0
 59 98  1  0
 60 62  1  0
 60 93  1  0
 61 63  1  0
 61 96  2  0
 61100  1  0
 62 64  1  0
 62100  1  0
 63 99  1  0
 64101  1  0
 65 66  1  0
 65101  1  0
 66 67  1  0
 67102  2  0
 67104  1  0
 68 74  1  0
 68106  1  0
 69 71  1  0
 69106  1  0
 70 72  1  0
 70 73  1  0
 71105  1  0
 72105  1  0
 73103  1  0
 73107  2  0
 74104  1  0
108112  2  0
109129  1  0
109119  2  0
110133  1  0
110103  1  0
111125  1  0
111149  1  0
113135  1  0
113145  2  0
113147  1  0
114134  2  0
114144  1  0
115149  1  0
115142  2  0
116136  1  0
116115  1  0
117138  1  0
117140  2  0
118139  1  0
119108  1  0
120135  1  0
120119  1  0
121118  1  0
122123  1  0
123116  1  0
124111  1  0
124146  2  0
124141  1  0
125121  1  0
126110  1  0
126136  1  0
126137  2  0
127112  1  0
127141  1  0
128117  1  0
129127  2  0
130139  1  0
130148  2  0
130143  1  0
131114  1  0
131147  1  0
132123  1  0
133128  1  0
M  RAD  8   1   3   2   3   3   3   4   3   5   3   6   3   7   3   8   3
M  RAD  8  11   2  12   3  13   3  14   3  15   3  16   3  21   3  24   2
M  RAD  8  25   2  26   3  28   3  29   2  30   2  31   2  35   3  36   3
M  RAD  8  37   3  38   2  41   2  42   2  44   3  45   3  46   3  49   2
M  RAD  8  50   2  51   3  52   3  53   3  54   3  55   3  56   3  58   3
M  RAD  8  60   3  62   2  63   3  64   3  65   3  66   3  68   3  69   3
M  RAD  8  70   3  71   3  72   3  74   3  76   2  80   2  81   2  82   2
M  RAD  8  83   2  87   2  89   2  95   2  97   2  98   3 100   2 103   2
M  RAD  8 104   2 108   2 109   2 110   2 111   2 112   2 116   2 118   3
M  RAD  8 120   3 121   3 122   2 123   2 125   3 128   3 129   2 131   3
M  RAD  8 132   2 133   3 136   2 138   2 139   2 141   2 143   3 144   2
M  RAD  2 147   2 149   2
M  END
$$$$
