Target Information

General Information of This Target (ID: PAYTAR0FLJAB)

Target Name	DNA topoisomerase 1 (TOP1)+Microtubule (MT)

Full List of The ADC Related to This Target

Phase 1

Click To Hide/Show 1 ADC Related to This Stage

ADC Name	Antibody	Antigen	Payload	Linker	ADC Info
JSKN021 ^[1]	Anti-EGFR/HER3 bsAb	Epidermal growth factor receptor (EGFR); Receptor tyrosine-protein kinase erbB-3 (HER3)	MMAE; Alphatecan	A cleavable linker	ADC Info

References

Ref 1	JSKN021, an innovative site-specific dual-payload bispecific antibody drug conjugate targeting EGFR and HER3 exhibits potent preclinical activities