Target Information

General Information of This Target

Target ID	PAYTAR0FLJAB
Target Name	DNA topoisomerase 1 (TOP1)+Microtubule (MT)

Full List of The ADC Related to This Target

Phase 1

Click To Hide/Show 1 ADC Related to This Stage

ADC Info	ADC Name	Antibody	Antigen	Payload	Linker	Ref
ADC Info	JSKN021	Anti-EGFR/HER3 bsAb	EGFR; HER3	MMAE; Alphatecan	A cleavable linker	[1]

References

Ref 1	JSKN021, an innovative site-specific dual-payload bispecific antibody drug conjugate targeting EGFR and HER3 exhibits potent preclinical activities