Target Information
General Information of This Target (ID: PATR0SDXWL)
| Target Name | Geranylgeranyl pyrophosphate synthase (GGPS1) |
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| Gene Name | GGPS1 |
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| Gene ID | ||||||
| Synonym | (2E,6E)-farnesyl diphosphate synthaseDimethylallyltranstransferaseFarnesyl diphosphate synthaseFarnesyltranstransferaseGeranylgeranyl diphosphate synthaseGeranyltranstransferase |
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| Sequence |
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNAS
LLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLL ELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTL GLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTEN IDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE Click to Show/Hide
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| Family | the FPP/GGPP synthase family |
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| Function |
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
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Full List of The ADC Related to This Target
Investigative
| ADC Name | Antibody | Antigen | Payload | Linker | ADC Info |
|---|---|---|---|---|---|
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Cet-ZA ADC
[1]
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Cetuximab |
Epidermal growth factor receptor (EGFR) |
Zoledronic acid |
Undisclosed |
References