Target Information

General Information of This Target
Target ID
PATR0JRULF
Target Name
Interferon alpha-1/13 (IFNA1; IFNA13)
Gene Name
IFNA1; IFNA13
Gene ID
3439 ; 3447
Synonym
Interferon alpha-D
Sequence
MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
LQERLRRKE

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Family
the alpha/beta interferon family
Function
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

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Uniprot Entry
IFNA1_HUMAN
HGNC ID
HGNC:5417 ; HGNC:5419
KEGG ID
hsa:3439 ; hsa:3447
Full List of The ADC Related to This Target
Investigative
Click To Hide/Show 1 ADC Related to This Stage
ADC Info ADC Name Antibody Antigen Payload Linker Ref
 ADC Info 
TAK-573
Undisclosed
CD38
Attenuated form of IFN alpha
Undisclosed
 [1]
References
Ref 1 TAK-573, an Anti-CD38/Attenuated Ifn Fusion Protein, Has Clinical Activity and Modulates the Ifn Receptor (IFNAR) Pathway in Patients with Relapsed/Refractory Multiple Myeloma. Blood (2020) 136 (Supplement 1): 37-38. doi: 10.1182/blood-2020-141219.

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