Target Information

General Information of This Target (ID: PATR0EDXOX)

Target Name	Bromodomain and extra-terminal (BET)

Full List of The ADC Related to This Target

Phase 1 (discontinued)

Click To Hide/Show 1 ADC Related to This Stage

ADC Name	Antibody	Antigen	Payload	Linker	ADC Info
ABBV-787 ^[1]	Anti-CD33 antibody	Myeloid cell surface antigen CD33 (CD33)	BET degrader	A cleavable linker	ADC Info

Investigative

Click To Hide/Show 1 ADC Related to This Stage

ADC Name	Antibody	Antigen	Payload	Linker	ADC Info
38467634 84-EBET ^[2]	#84.7	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)	EBET-1055	Undisclosed	ADC Info

References

Ref 1	anti-CD33/BET degrader ADC ABBV-787
Ref 2	Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models