Payload Information
General Information of This Payload
| Payload ID | PAY0ZVTBM |
|||||
|---|---|---|---|---|---|---|
| Name | AU2020291014A1-Payload-17 |
|||||
| Synonyms |
AU2020291014A1-Payload-17
Click to Show/Hide
|
|||||
| Structure |
|
|||||
| Formula | C29H39N5O4S |
|||||
| Isosmiles | CCCN(CCCCCN)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C3=CC(S(=O)(N4CC(C4)CO)=O)=CC=C3)=O |
|||||
| InChI |
InChI=1S/C29H39N5O4S/c1-2-12-33(13-5-3-4-11-30)29(36)25-14-24-10-9-23(16-27(24)32-28(31)17-25)22-7-6-8-26(15-22)39(37,38)34-18-21(19-34)20-35/h6-10,14-16,21,35H,2-5,11-13,17-20,30H2,1H3,(H2,31,32)
|
|||||
| InChIKey |
LHCCCJIQQRPRGT-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties | Molecule Weight |
553.729 |
Polar area |
142.32 |
||
Complexity |
1303.557056 |
xlogp Value |
3.1098 |
|||
Heavy Count |
39 |
Rot Bonds |
12 |
|||
Hbond acc |
7 |
Hbond Donor |
3 |
|||
Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-11 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
|
||||
| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||