Payload Information

General Information of This Payload
Payload ID
PAY0WCNDB
Name
I030
Target IKZF1/3
 Target Info 
Structure
Isosmiles
O=C1NC(CCC1N(C(C2=CC=CC3=C42)=O)C4=CC=C3CC5=CN(C6CCNCC6)N=C5)=O
The activity data of This Payload
Standard Type Value Units Cell line Disease Model Cell line ID Reference
Half Maximal Inhibitory Concentration (IC50) 0.16 nM
NCI-H929 cells
Multiple myeloma
CVCL_1600 
Half Maximal Degradation Concentration (DC50) 0.256 nM
MM.1S cells
Multiple myeloma
CVCL_8792 
Each Antibody-drug Conjugate Related to This Payload