Payload Information
General Information of This Payload
| Payload ID | PAY0TVSSL |
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|---|---|---|---|---|---|---|
| Name | KRM-1657 |
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| Synonyms |
KRM-1657
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| Formula | C50H62N4O13 |
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| Isosmiles | CCCN1CCN(CC1)C2=CC(=O)C3=NC4=C5C6=C(C(=C7C5=C([C@](O7)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]([C@H](/C=C/C=C(\C(=O)NC(=C4OC3=C2)C6=O)/C)C)O)C)O)C)OC(=O)C)C)OC)C)O)C)O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C50H62N4O13/c1-11-16-53-17-19-54(20-18-53)31-22-32(56)38-34(23-31)66-47-39(51-38)35-36-43(59)29(7)46-37(35)48(61)50(9,67-46)64-21-15-33(63-10)26(4)45(65-30(8)55)28(6)42(58)27(5)41(57)24(2)13-12-14-25(3)49(62)52-40(47)44(36)60/h12-15,21-24,26-28,33,41-42,45,57-59,61H,11,16-20H2,1-10H3,(H,52,62)/t24-,26+,27+,28+,33-,41-,42+,45+,50-/m0/s1
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| InChIKey |
ZODCXYAIOGQHKM-DHKOKREGSA-N
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| Pharmaceutical Properties | Molecule Weight |
927.061 |
Polar area |
230.66 |
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Complexity |
2798.335551 |
xlogp Value |
5.09212 |
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Heavy Count |
67 |
Rot Bonds |
5 |
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Hbond acc |
16 |
Hbond Donor |
5 |
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The activity data of This Payload
| Standard Type | Value | Units | Cell line | Disease Model | Cell line ID | Reference |
|---|---|---|---|---|---|---|
| Cellular activity | 0 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0.79 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0.84 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 0.97 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 1.3 | pmol | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 245 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 298 | pg | Undisclosed | Undisclosed | Undisclosed | |
| Cellular activity | 369 | pg | Undisclosed | Undisclosed | Undisclosed |
Each Antibody-drug Conjugate Related to This Payload