Payload Information

General Information of This Payload

Payload ID	PAY0STTRW
Name	Macrocyclic antimicrobial peptide 3C (AMP-3C)
Synonyms	Macrocyclic antimicrobial peptide 3C (AMP-3C) Click to Show/Hide
Target(s)	.	Target Info

Each Antibody-drug Conjugate Related to This Payload

Full Information of The Activity Data of The ADC(s) Related to This Payload

ABC-3C [Investigative]

ADC Info

Revealed Based on the Cell Line Data

Click To Hide/Show 2 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC				[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	40.00 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)	.
Experiment 2 Reporting the Activity Date of This ADC				[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	170 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)	.

References

Ref 1	Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. Chembiochem. 2018 Oct 4;19(19):2039-2044. doi: 10.1002/cbic.201800295. Epub 2018 Sep 14.

If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.