Payload Information

General Information of This Payload

Payload ID	PAY0SKLCH
Name	Macrocyclic antimicrobial peptide 3E (AMP-3E)
Synonyms	Macrocyclic antimicrobial peptide 3E (AMP-3E) Click to Show/Hide
Target(s)	.	Target Info

Each Antibody-drug Conjugate Related to This Payload

Full Information of The Activity Data of The ADC(s) Related to This Payload

ABC-3E [Investigative]

ADC Info

Revealed Based on the Cell Line Data

Click To Hide/Show 2 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC				[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	> 1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 1 (E. coli 1)	.
Experiment 2 Reporting the Activity Date of This ADC				[1]
Efficacy Data	Half Maximal Effective Concentration (EC50)	> 1000 nM
Method Description	Bacterial killing potencies and hemolytic activities of prepared ABCs. MKC 50 represents the minimal concentration to impart >50 % killing.
In Vitro Model	.	Escherichia coli 2 (E. coli 2)	.

References

Ref 1	Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria. Chembiochem. 2018 Oct 4;19(19):2039-2044. doi: 10.1002/cbic.201800295. Epub 2018 Sep 14.

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