Payload Information
General Information of This Payload (ID: PAY0SDRFH)
| Name |
Amine-I034
|
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|---|---|---|---|---|---|---|
| Target | IKZF1/3 | |||||
| Isosmiles | NC1(CCC1)C(N2CCC(N3C=C(CC4=CC=C5N(C(C6=CC=CC4=C56)=O)C7CCC(NC7=O)=O)C=N3)CC2)=O |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
αCD38-MC-I034 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Inhibitory Concentration (IC50) |
0.022 nM
|
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| In Vitro Model | Plasma cell myeloma | NCI-H929 cells | CVCL_1600 | ||
αBCMA-MC-I034 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Inhibitory Concentration (IC50) |
0.046 nM
|
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| In Vitro Model | Plasma cell myeloma | NCI-H929 cells | CVCL_1600 | ||
References