Payload Information
General Information of This Payload
| Payload ID | PAY0QVZMF |
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| Name | AU2020291014A1-Payload-27 |
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| Synonyms |
AU2020291014A1-Payload-27
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| Structure |
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| Formula | C34H45N7O6 |
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| Isosmiles | CCCN(CCCNC(OC(C)(C)C)=O)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C(NC3=CN=C(N4CCC(CC4)C(O)=O)C=C3)=O)=O |
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| InChI |
InChI=1S/C34H45N7O6/c1-5-14-41(15-6-13-36-33(46)47-34(2,3)4)31(43)25-18-23-7-8-24(19-27(23)39-28(35)20-25)30(42)38-26-9-10-29(37-21-26)40-16-11-22(12-17-40)32(44)45/h7-10,18-19,21-22H,5-6,11-17,20H2,1-4H3,(H2,35,39)(H,36,46)(H,38,42)(H,44,45)
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| InChIKey |
GVQDPXFRZHQOIY-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
647.777 |
Polar area |
179.55 |
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Complexity |
1469.423149 |
xlogp Value |
4.5641 |
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Heavy Count |
47 |
Rot Bonds |
11 |
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Hbond acc |
9 |
Hbond Donor |
4 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-19 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||