Payload Information
General Information of This Payload
| Payload ID | PAY0QFTZO |
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| Name | AU2020291014A1-Payload-3 |
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| Synonyms |
AU2020291014A1-Payload-3
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| Structure |
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| Formula | C29H39N5O4S |
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| Isosmiles | CNCC1=C(S(N2CC(C2)CO)(=O)=O)C=C(C3=CC4=C(C=C(C(N(CCC)CCC)=O)CC(N)=N4)C=C3)C=C1 |
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| InChI |
InChI=1S/C29H39N5O4S/c1-4-10-33(11-5-2)29(36)25-12-23-8-6-21(13-26(23)32-28(30)15-25)22-7-9-24(16-31-3)27(14-22)39(37,38)34-17-20(18-34)19-35/h6-9,12-14,20,31,35H,4-5,10-11,15-19H2,1-3H3,(H2,30,32)
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| InChIKey |
VCCGBNIYGQWFSP-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
553.729 |
Polar area |
128.33 |
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Complexity |
1328.402298 |
xlogp Value |
3.1102 |
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Heavy Count |
39 |
Rot Bonds |
11 |
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Hbond acc |
7 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-2 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
14.8 nM
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| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||