Payload Information
General Information of This Payload
| Payload ID | PAY0QESNA |
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| Name | AU2020291014A1-Payload-18 |
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| Synonyms |
AU2020291014A1-Payload-18
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| Structure |
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| Formula | C24H30N6O2 |
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| Isosmiles | CCCN(CCC)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C(NC3=CN=CC(CN)=C3)=O)=O |
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| InChI |
InChI=1S/C24H30N6O2/c1-3-7-30(8-4-2)24(32)19-10-17-5-6-18(11-21(17)29-22(26)12-19)23(31)28-20-9-16(13-25)14-27-15-20/h5-6,9-11,14-15H,3-4,7-8,12-13,25H2,1-2H3,(H2,26,29)(H,28,31)
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| InChIKey |
ONKSYRCJTVQULQ-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
434.544 |
Polar area |
126.7 |
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Complexity |
1021.753881 |
xlogp Value |
3.217 |
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Heavy Count |
32 |
Rot Bonds |
8 |
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Hbond acc |
6 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-12 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||