Payload Information

General Information of This Payload
Payload ID
PAY0PSFMW
Name
P297
Synonyms
P297
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The activity data of This Payload
Standard Type Value Units Cell line Disease Model Cell line ID Reference
Half Maximal Inhibitory Concentration (IC50) 0.04 ug/ml
Pae27853
P. aeruginosa strains
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.04 ug/ml
Pae27853
P. aeruginosa strains
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.07 ug/ml
BAA-2114
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.07 ug/ml
BAA-2114
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.28 ug/ml
BAA-2110
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.28 ug/ml
BAA-2110
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.28 ug/ml
BAA-2108
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Half Maximal Inhibitory Concentration (IC50) 0.28 ug/ml
BAA-2108
Pseudomonas aeruginosa (Schroeter) Migula
Undisclosed [1]
Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
ES2994374T3 conjugate5 [Investigative]
 ADC Info 
Revealed Based on the Cell Line Data
Click To Hide/Show 2 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
0.4 ug/ml
Method Description
Conjugates were tested in Pae39324, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model P. aeruginosa strains Pae39324 .
Experiment 2 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
1.6 ug/ml
Method Description
Conjugates were tested in Pae27853, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model P. aeruginosa strains Pae27853 .
mAb001-Conjugate2 [Investigative]
 ADC Info 
Revealed Based on the Cell Line Data
Click To Hide/Show 4 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
3.1 ug/ml
Method Description
Conjugates were tested in BAA-2114, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model Pseudomonas aeruginosa (Schroeter) Migula BAA-2114 Pseudomonas aeruginosa (Schroeter) Migula
Experiment 2 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
3.1 ug/ml
Method Description
Conjugates were tested in BAA-2108, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model Pseudomonas aeruginosa (Schroeter) Migula BAA-2108 Pseudomonas aeruginosa (Schroeter) Migula
Experiment 3 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
3.3 ug/ml
Method Description
Conjugates were tested in Pae27853, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model P. aeruginosa strains Pae27853 .
Experiment 4 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (lC50)
6.3 ug/ml
Method Description
Conjugates were tested in BAA-2110, diluted and loaded into a 96 well polypropylene microtiter plate. Then the microtiter plate was incubated at 37°C overnight.
In Vitro Model Pseudomonas aeruginosa (Schroeter) Migula BAA-2110 Pseudomonas aeruginosa (Schroeter) Migula
References
Ref 1 Antibody molecule-drug conjugates and uses thereof