Payload Information
General Information of This Payload
| Payload ID | PAY0NTXJX |
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| Name | AU2020291014A1-Payload-2 |
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| Synonyms |
AU2020291014A1-Payload-2
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| Structure |
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| Formula | C27H34N4O4S |
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| Isosmiles | CCCN(CCC)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C3=CC(S(=O)(N4CC(C4)CO)=O)=CC=C3)=O |
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| InChI |
InChI=1S/C27H34N4O4S/c1-3-10-30(11-4-2)27(33)23-12-22-9-8-21(14-25(22)29-26(28)15-23)20-6-5-7-24(13-20)36(34,35)31-16-19(17-31)18-32/h5-9,12-14,19,32H,3-4,10-11,15-18H2,1-2H3,(H2,28,29)
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| InChIKey |
ZLDDGAXHLAIMJL-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
510.66 |
Polar area |
116.3 |
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Complexity |
1248.866646 |
xlogp Value |
3.3908 |
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Heavy Count |
36 |
Rot Bonds |
9 |
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Hbond acc |
6 |
Hbond Donor |
2 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-1 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||
AU2020291014A1 IC-3 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||
AU2020291014A1 IC-4 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||