Payload Information
General Information of This Payload
| Payload ID | PAY0MKANG |
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| Name | AU2020291014A1-Payload-19 |
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| Synonyms |
AU2020291014A1-Payload-19
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| Structure |
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| Formula | C31H43N5O4S |
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| Isosmiles | CCCN(CCC)C(C(CC(N)=N1)=CC2=C1C=C(C=C2CCCCN)C3=CC(S(N4CC(C4)CO)(=O)=O)=CC=C3)=O |
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| InChI |
InChI=1S/C31H43N5O4S/c1-3-12-35(13-4-2)31(38)26-16-28-24(8-5-6-11-32)14-25(17-29(28)34-30(33)18-26)23-9-7-10-27(15-23)41(39,40)36-19-22(20-36)21-37/h7,9-10,14-17,22,37H,3-6,8,11-13,18-21,32H2,1-2H3,(H2,33,34)
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| InChIKey |
HPNOCSAODILKTD-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
581.783 |
Polar area |
142.32 |
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Complexity |
1361.111831 |
xlogp Value |
3.6722 |
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Heavy Count |
41 |
Rot Bonds |
13 |
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Hbond acc |
7 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-13 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||