Payload Information
General Information of This Payload
| Payload ID | PAY0JBSYM |
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|---|---|---|---|---|---|---|
| Name | TLR7 agonist-2 |
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| Synonyms |
TLR7 agonist-2
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| Target(s) | Toll-like receptor 7 (TLR7) | |||||
| Structure |
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| Formula | C22H25N5 |
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| Isosmiles | CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1 |
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| InChI |
InChI=1S/C22H25N5/c1-2-3-8-19-26-20-21(17-6-4-5-7-18(17)25-22(20)24)27(19)14-16-11-9-15(13-23)10-12-16/h4-7,9-12H,2-3,8,13-14,23H2,1H3,(H2,24,25)
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| InChIKey |
SDSKFWHQCNBICO-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
359.477 |
Polar area |
82.75 |
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Complexity |
27 |
xlogp Value |
4.0163 |
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Heavy Count |
27 |
Rot Bonds |
6 |
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Hbond acc |
5 |
Hbond Donor |
2 |
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The activity data of This Payload
| Standard Type | Value | Units | Cell line | Disease Model | Cell line ID | Reference |
|---|---|---|---|---|---|---|
| IFNalpha induction level | ≈245 | pg/mL |
Human peripheral blood mononuclear cells(hPBMCs)
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Normal
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[1] |
Each Antibody-drug Conjugate Related to This Payload
References
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