Payload Information
General Information of This Payload
| Payload ID | PAY0FQSFC |
|||||
|---|---|---|---|---|---|---|
| Name | AU2020291014A1-Payload-16 |
|||||
| Synonyms |
AU2020291014A1-Payload-16
Click to Show/Hide
|
|||||
| Structure |
|
|||||
| Formula | C29H36N6O4 |
|||||
| Isosmiles | CCCN(CCC)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C(NC3=CN=C(N4CCC(CC4)C(O)=O)C=C3)=O)=O |
|||||
| InChI |
InChI=1S/C29H36N6O4/c1-3-11-35(12-4-2)28(37)22-15-20-5-6-21(16-24(20)33-25(30)17-22)27(36)32-23-7-8-26(31-18-23)34-13-9-19(10-14-34)29(38)39/h5-8,15-16,18-19H,3-4,9-14,17H2,1-2H3,(H2,30,33)(H,32,36)(H,38,39)
|
|||||
| InChIKey |
ZSGWTNNFMGUWMF-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties | Molecule Weight |
532.645 |
Polar area |
141.22 |
||
Complexity |
1231.443556 |
xlogp Value |
4.0593 |
|||
Heavy Count |
39 |
Rot Bonds |
9 |
|||
Hbond acc |
7 |
Hbond Donor |
3 |
|||
Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-10 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
|
||||
| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||