Payload Information
General Information of This Payload
| Payload ID | PAY0BJVTL |
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| Name | AU2020291014A1-Payload-33 |
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| Synonyms |
AU2020291014A1-Payload-33
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| Structure |
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| Formula | C27H35N5O4S |
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| Isosmiles | CCCN(CCCN)C(C(CC(N)=N1)=CC2=C1C=C(C=C2)C3=CC(S(N4CC(C4)CO)(=O)=O)=CC=C3)=O |
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| InChI |
InChI=1S/C27H35N5O4S/c1-2-10-31(11-4-9-28)27(34)23-12-22-8-7-21(14-25(22)30-26(29)15-23)20-5-3-6-24(13-20)37(35,36)32-16-19(17-32)18-33/h3,5-8,12-14,19,33H,2,4,9-11,15-18,28H2,1H3,(H2,29,30)
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| InChIKey |
KLONZNNRVYTGNO-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
525.675 |
Polar area |
142.32 |
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Complexity |
1271.068447 |
xlogp Value |
2.3296 |
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Heavy Count |
37 |
Rot Bonds |
10 |
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Hbond acc |
7 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
AU2020291014A1 IC-22 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) | > 1000 nM | |||
| Method Description |
Mycloid TNFa Secretion
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| In Vitro Model | Mycloid | Mycloid cells | Homo sapiens | ||