Linker Information
General Information of This Linker
| Linker ID |
LIN0ZZAHM
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|---|---|---|---|---|---|---|
| Linker Name |
CN106714844B-ADC-103-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C13H19N3O4S2
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| Isosmiles |
CN(CCN(C)C(OCCSSC1=NC=CC=C1)=O)C(O)=O
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| InChI |
InChI=1S/C13H19N3O4S2/c1-15(12(17)18)7-8-16(2)13(19)20-9-10-21-22-11-5-3-4-6-14-11/h3-6H,7-10H2,1-2H3,(H,17,18)
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| InChIKey |
OQHDAZSYORCOON-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
345.446
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Polar area
|
82.97
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Complexity
|
440.3659316
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xlogp Value
|
2.5001
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Heavy Count
|
22
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Rot Bonds
|
8
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Hbond acc
|
6
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker