Linker Information
General Information of This Linker
| Linker ID |
LIN0ZXGQK
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| Linker Name |
CN112604004B-SCT-200-R-1-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H45N7O8
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(CCC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NCC(N(CCC2)C2C=O)=O)=O)=O)C
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| InChI |
InChI=1S/C28H45N7O8/c1-18(2)25(33-21(37)10-4-3-5-14-35-22(38)11-12-23(35)39)27(42)32-20(9-6-13-30-28(29)43)26(41)31-16-24(40)34-15-7-8-19(34)17-36/h17-20,25H,3-16H2,1-2H3,(H,31,41)(H,32,42)(H,33,37)(H3,29,30,43)/t19?,20-,25-/m0/s1
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| InChIKey |
GHNPTDPADJJVHC-FZNKQFQNSA-N
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| Pharmaceutical Properties |
Molecule Weight
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607.709
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Polar area
|
217.18
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Complexity
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979.0557005
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xlogp Value
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-0.924
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Heavy Count
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43
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Rot Bonds
|
18
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Hbond acc
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8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker