General Information of This Linker
Linker ID
LIN0ZWUZC
Linker Name
LD1 linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C18H29N3O6
Isosmiles
CC([C@H](NC(CCCCCN1C(CCC1=O)=O)=O)C(N[C@@H](C)C(O)=O)=O)C
InChI
InChI=1S/C18H29N3O6/c1-11(2)16(17(25)19-12(3)18(26)27)20-13(22)7-5-4-6-10-21-14(23)8-9-15(21)24/h11-12,16H,4-10H2,1-3H3,(H,19,25)(H,20,22)(H,26,27)/t12-,16-/m0/s1
InChIKey
WTOWPRQPYOMHKL-LRDDRELGSA-N
Pharmaceutical Properties
Molecule Weight
383.445
Polar area
132.88
Complexity
540.5873849
xlogp Value
0.4259
Heavy Count
27
Rot Bonds
11
Hbond acc
5
Hbond Donor
3
Each Antibody-drug Conjugate Related to This Linker