Linker Information
General Information of This Linker
| Linker ID |
LIN0ZPAFG
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| Linker Name |
TW202506738A-C-111-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H43N7O18S
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| Isosmiles |
C[C@H](NC(CNC(CNC(CNC(CCN(S(CCOCCOOOOOOOOC)(=O)=O)CCN1C(C=CC1=O)=O)=O)=O)=O)=O)C(NC(C=C2)=CC=C2C)=O
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| InChI |
InChI=1S/C30H43N7O18S/c1-21-4-6-23(7-5-21)35-30(44)22(2)34-27(41)20-33-26(40)19-32-25(39)18-31-24(38)10-11-36(12-13-37-28(42)8-9-29(37)43)56(45,46)17-16-48-14-15-49-51-53-55-54-52-50-47-3/h4-9,22H,10-20H2,1-3H3,(H,31,38)(H,32,39)(H,33,40)(H,34,41)(H,35,44)/t22-/m0/s1
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| InChIKey |
NGPWDGIQGZRPNQ-QFIPXVFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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821.772
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Polar area
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303.33
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Complexity
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1510.771927
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xlogp Value
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-3.08208
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Heavy Count
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56
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Rot Bonds
|
29
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Hbond acc
|
18
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker