Linker Information
General Information of This Linker
| Linker ID |
LIN0ZNJWN
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| Linker Name |
MP-Asn-Cit-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H41N9O11
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| Isosmiles |
O=C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](CC(N)=O)NC(CCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C34H41N9O11/c1-42(34(52)53)25-7-3-2-5-21(25)18-38-33(51)54-19-20-8-10-22(11-9-20)39-30(48)23(6-4-15-37-32(36)50)41-31(49)24(17-26(35)44)40-27(45)14-16-43-28(46)12-13-29(43)47/h2-3,5,7-13,23-24H,4,6,14-19H2,1H3,(H2,35,44)(H,38,51)(H,39,48)(H,40,45)(H,41,49)(H,52,53)(H3,36,37,50)/t23-,24-/m0/s1
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| InChIKey |
NZINEGCDZSKHKN-ZEQRLZLVSA-N
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| Pharmaceutical Properties |
Molecule Weight
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751.754
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Polar area
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301.76
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Complexity
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1692.955653
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xlogp Value
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-0.2257
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Heavy Count
|
54
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Rot Bonds
|
19
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Hbond acc
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10
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Hbond Donor
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8
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Each Antibody-drug Conjugate Related to This Linker